Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Heart failure medication falls short of primary endpoint in phase 3 trial

Novartis announced that a phase 3 study evaluating the company’s investigational heart failure medication (serelaxin) did not meet its primary endpoint.

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ACC.17: Medicare beneficiaries implanted with CardioMEMS system have lower rate of heart failure hospitalizations

Medicare beneficiaries who received an implantable pulmonary artery pressure (PAP) sensor had a statistically significant 45 percent lower rate of heart failure hospitalizations and reduced costs at six months, according to a retrospective cohort study.

ACC.17: Detroit cardiologists increase cardiogenic shock survival rate to 84% using Abiomed heart pump

A coalition of medical centers in southeast Michigan have found a way to increase the survival rate of cardiogenic shock patients to 84 percent by using a heart pump manufactured by Danvers, Massachusetts-based Abiomed. 

Test may help identify risk of acute kidney injury in heart failure patients

An analysis of patients in the emergency department at a hospital in Germany found that using the NephroCheck Test could help identify the risk of acute kidney injury in patients with acute decompensated heart failure.

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ACC.17: Research at ACC shows that marijuana increases risk for heart failure, stroke

Though cannabis has increasingly been making its way into healthcare as a method for treating a series of conditions, new research on the drug, presented at the American College of Cardiology (ACC)’s Scientific Session beginning March 17, finds that it could cause severe cardiovascular events.

New Prevention Strategy for Heart Disease

SDSU researcher uncovers molecular pathway that protects the heart from damage during a heart attack.

Influence of Cardiac Arrest and Cardiogenic Shock on Outcomes in STEMI Patients

Minneapolis Heart Institute Foundation® study finds that presence of cardiac arrest and/or cardiogenic shock is responsible for more than 75% of hospital deaths in STEMI patients

Being overweight, obese could spell heart disease at a younger age

Being overweight or obese could increase an individual’s chances of developing cardiovascular disease at a younger age compared to those who maintain more healthy weights, according to new research. 

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Around the web

Health Imaging
Use of AI opportunistic screening in CT for cardiovascular disease

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Health Imaging
New imaging protocols proposed to curb rise of cardiovascular infections

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.