Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

COVID-19 vaccines helped heart failure patients stay out of the hospital and live longer
Vaccination was linked to key benefits in terms of all-cause mortality, heart failure hospitalizations, stroke, heart attack, myocarditis, venous thromboembolism and testing positive for COVID-19.
Cardiologists and surgeons perform world’s first robot-assisted TEER
A 62-year-old women presented with severe MR and recurrent heart failure episodes. Initial data suggest the procedure was a success.
Confirmed: AFib ablation more beneficial for patients with HFrEF than those with HFpEF
Researchers explored data from nearly 2,500 AFib ablation patients, sharing their findings in JAMA Cardiology.
Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke
All participants were free of ASCVD and had no history of statin use at the start of the study.
Diabetic cardiomyopathy treatment shows promise in ARISE-HF
James Januzzi Jr., MD, said the treatment's overall impact was neutral, but he and his team saw "a very clear and encouraging signal."

Dihydropyridines such as amlodipine have been the topic of some debate in recent months due to fears they lead to significant side effects.

October 13, 2023

High-risk percutaneous coronary intervention (PCI) with an Impella heart pump is associated with better outcomes, including a significantly higher survival rate, than high-risk PCI with an intra-aortic balloon pump (IABP), according to new findings published in the American Journal of Cardiology. Impella Heart Pump Abiomed RECOVER IV RCT cardiogenic shock

FDA warns Abiomed about ‘significant violations’ related to its Impella heart pumps

The agency said Abiomed did not seek the necessary approvals for one Impella-related device and was slow to act on certain safety concerns.

October 12, 2023

Endotronix gains key approval from FDA, shares new heart failure data

The company can now begin the enrollment process for its PROACTIVE-HF 2 clinical trial, which will focus on treating patients with NYHA class II heart failure.

October 11, 2023

CBD could be beneficial for some heart failure patients

The subcutaneous administration of CBD could make a significant impact on patient outcomes, according to new findings presented at the Heart Failure Society of America's annual meeting in Cleveland.

October 10, 2023

Patisiran, marketed under the name Onpattro

FDA chooses not to approve patisiran for treating ATTR cardiomyopathy

The announcement came just weeks after an FDA subcommittee voted in favor of approval.

October 9, 2023

Elderly patient doctor. Despite an expanded indication from the FDA and lower prices, patient access to these cholesterol-lowering medications remains a significant issue.

What is CKM syndrome? American Heart Association outlines how to identify and manage a dangerous new condition

The American Heart Association has developed an updated strategy for the prevention and management of cardiovascular disease. A newly defined health condition, cardiovascular-kidney-metabolic syndrome, sits at the center of that strategy.

October 9, 2023

Artificial intelligence (AI) is being developed to help make cardiovascular clinical trials more efficient, lead to faster advances in patient care, and bring possible new treatments to heart patients more quickly. The major cardiac research center of Icahn School of Medicine at Mount Sinai announced today that it signed a memorandum of understanding with the Chiba Institute of Technology (CIT) to collaborate on using AI to enhance cardiovascular disease research.

Mount Sinai partners with the Chiba Institute of Technology on AI to transform cardiovascular research

Agreement aims to use AI to help make cardiology clinical trials more efficient and lead to faster advances in patient care.

October 5, 2023

AI artificial intelligence stethoscope doctor

FDA clears AI model for detecting signs of heart failure in ECGs

The advanced AI model, developed by Anumana with help from Mayo Clinic, could provide value as a screening tool for heart failure.

October 2, 2023

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Heart Failure

COVID-19 vaccines helped heart failure patients stay out of the hospital and live longer

Cardiologists and surgeons perform world’s first robot-assisted TEER

Confirmed: AFib ablation more beneficial for patients with HFrEF than those with HFpEF

Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke

Diabetic cardiomyopathy treatment shows promise in ARISE-HF

Around the web