Genetic aversion to metabolize fructose may ward off obesity, diabetes
People with essential fructosuria, a rare genetic mutation, don’t have the enzyme needed to metabolize fructose, found in honey, fruits and vegetables. The benefit? Little to no risk of developing obesity or type 2 diabetes, reports Bloomberg.
Fructose is generally associated with weight gain and increases risk for metabolic syndrome.
Researchers and pharmaceutical companies are looking to better understand weight-related conditions and to also treat people who suffer from obesity. Some pharmaceutical executives even hope to prevent insulin resistance and obesity.
The mutation could be helpful in developing potential treatments. The problem? Only one in 130,000 people has it.
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