Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

The most successful case to date of a pig organ being transplanted into a human occurred back in January, when specialists at the University of Maryland Medical Center (UMMC) in Baltimore transplanted a modified pig heart into 57-year-old David Bennett. The FDA approved the heart transplant transplant through an emergency authorization typically reserved for experimental procedures seen as a patient’s last chance at survival. Bennett did die of heart failure two months later.#pigheart

Multiple specialists involved in the procedure, including the surgeon who transplanted the pig heart, are scheduled to speak at the conference. 

Three recent NIH-supported studies took a close look at disparities in cardiovascular care.

A patient has a telehealth visit with their doctor remotely in their home via video conferencing. The COVID-19 cause massive movement to telehealth since 2020.

Following medical discharge, a program consisting of at-home visits, telehealth appointments and clinic visits resulted in better outcomes and lower healthcare costs than typical post-discharge care.

Bodyport, a San Francisco-based healthcare technology company focused on detecting cardiovascular disease, has received U.S. Food and Drug Administration (FDA) clearance for a new digital scale that can help monitor fluid retention and enable earlier interventions in heart failure management.

The newly cleared device works like a traditional scale, but it captures more data than just the user's weight. 

The Harmony pulmonary valve was among the devices involved with the FDA Breakthrough Device Designation program that gained more rapid market clearance. The FDA graph shows cardiovascular devices leading the types of devices involved in the program.

The FDA said cardiovascular devices make up the largest number of technologies accepted into the Breakthrough Devices Program, and several are on the list of the first 50 in the program to gain market clearance.

This latest shortage involves dobutamine, an injectable medication often prescribed for advanced heart failure and cardiogenic shock. It is also a central component of dobutamine stress echocardiography (DSE), a test used to evaluate patients with severe aortic stenosis.

The shortage could lead to significant issues for cardiologists. The American College of Cardiology provided some words of wisdom on the ongoing issue.  


New data from the CDC and U.S. Census Bureau show just how bad CVD rates could get in the next few decades. Specialists agree that a lot of work is needed to help keep these estimates from becoming a reality. 

After staying mostly consistent between 1999 and 2012, age-adjusted mortality rates rose sharply through 2019. 

Ancora Heart AccuCinch Ventricular Restoration System heart failure FDA

Ancora Heart received the FDA’s breakthrough device designation for its AccuCinch Ventricular Restoration System, a new minimally invasive transcatheter device designed for the treatment of heart failure.


Limiting salt is a common recommendation for patients hoping to improve their heart health or lose weight. According to a new analysis of more than 1,700 patients, however, going too far with such restrictions can lead to worse outcomes. 

The American Heart Association and Association of Black Cardiologists announced the winners of a six-month data challenge, describing health equity as "one of the most pressing areas in healthcare.”

Researchers tracked data from more than 450,000 patients treated over the course of 15 years, sharing their findings in JAMA Network Open.

Around the web

Two companies serving medical imagers just had products cleared for marketing in the U.S.

Defendants in the case allegedly defrauded CMS for millions of dollars that were spent on luxury vehicles, real estate and more.

Surgeons at NYU Langone Health successfully transplanted two genetically engineered pigs hearts into recently deceased humans in June and July.

Trimed Popup
Trimed Popup