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Gene-editing therapy for heart patients impresses | Prosthesis-patient mismatch & TAVR: A new perspective

News You Need to Know Today
Gene-editing therapy for heart patients impresses | Prosthesis-patient mismatch & TAVR: A new perspective
Monday, November 20, 2023
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Today's News and Trends

Gene-editing therapy lowers cholesterol in high-risk heart patients—one dose could potentially last decades

While the therapy has been successfully tested on animals in the past, this study represents the first time it has been used on humans.

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A new gene-editing therapy has been tested on humans for the first time, resulting in a significant reduction in their low-density lipoprotein (LDL) cholesterol that could potentially last for decades. The study’s authors presented these early results at the AHA 2023 meeting.
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Gene-editing therapy lowers cholesterol in high-risk heart patients—one dose could potentially last decades

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A new gene-editing therapy has been tested on humans for the first time, resulting in a significant reduction in their low-density lipoprotein (LDL) cholesterol that could potentially last for decades. The study’s authors presented these early results at the AHA 2023 meeting.
While the therapy has been successfully tested on animals in the past, this study represents the first time it has been used on humans.
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Cardiologists may want to rethink how they track prosthesis-patient mismatch after TAVR

Researchers evaluated two techniques for predicting PPM after TAVR, comparing them to how cardiologists typically check for PPM in day-to-day practice. 

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The Bern TAVI Registry looked at 2,500 TAVR patients to determine the level of prosthesis-patient mismatch (PPM) using transthoracic echocardiography (TTE), predicting PPM based one the size of the valve used, or using CT measurements of the aortic annulus to see which was method was most accurate at predicting PPM. Image courtesy of Tomii et al. 
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Cardiologists may want to rethink how they track prosthesis-patient mismatch after TAVR

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The Bern TAVI Registry looked at 2,500 TAVR patients to determine the level of prosthesis-patient mismatch (PPM) using transthoracic echocardiography (TTE), predicting PPM based one the size of the valve used, or using CT measurements of the aortic annulus to see which was method was most accurate at predicting PPM. Image courtesy of Tomii et al. 
Researchers evaluated two techniques for predicting PPM after TAVR, comparing them to how cardiologists typically check for PPM in day-to-day practice. 
READ MORE >

Featured Articles

Daily marijuana use increases heart failure risk by 34%

“Marijuana use isn’t without its health concerns, and our study provides more data linking its use to cardiovascular conditions," one researcher said. 

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cannabis use disorder marijuana joint weed smoking
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Daily marijuana use increases heart failure risk by 34%

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cannabis use disorder marijuana joint weed smoking
“Marijuana use isn’t without its health concerns, and our study provides more data linking its use to cardiovascular conditions," one researcher said. 
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ChatGPT struggles with echocardiography, but still shows potential to help cardiology trainees

ChatGPT may not be quite ready to help prepare trainees for their next echocardiography exam—but it does show promise. 

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artificial intelligence AI heart cardiology
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ChatGPT struggles with echocardiography, but still shows potential to help cardiology trainees

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artificial intelligence AI heart cardiology
ChatGPT may not be quite ready to help prepare trainees for their next echocardiography exam—but it does show promise. 
READ MORE >

The expanding scope of FDG-PET in nuclear cardiac imaging

Jamie Bourque, MD, spoke to Cardiovascular Business about the growing number of ways FDG-PET scans are being used in cardiology. This includes evaluating inflammation, tracking EP device infections and much more. 

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Jamie Bourque, MD, discusses fluorodeoxyglucose (FDG) and its growing use cases in cardiac PET imaging He discussed the radiotracer in sessions at ASNC 2023. #ASNC #ASNC23 #ASNC2023
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The expanding scope of FDG-PET in nuclear cardiac imaging

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Jamie Bourque, MD, discusses fluorodeoxyglucose (FDG) and its growing use cases in cardiac PET imaging He discussed the radiotracer in sessions at ASNC 2023. #ASNC #ASNC23 #ASNC2023
Jamie Bourque, MD, spoke to Cardiovascular Business about the growing number of ways FDG-PET scans are being used in cardiology. This includes evaluating inflammation, tracking EP device infections and much more. 
READ MORE >

In Case You Missed It

FDA approves first renal denervation system for uncontrolled hypertension

The system, designed for patients with uncontrolled hypertension who are unresponsive to medication, uses ultrasound ablation to target nerves in the renal arteries, increasing blood flow. This approval comes just months after an FDA advisory panel voted in favor of the system. 

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The U.S. Food and Drug Administration (FDA) has approved Recor Medical’s Paradise Ultrasound Renal Denervation (RDN) system for uncontrolled hypertension. The Recor system gained FDA clearance in November 2023.
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FDA approves first renal denervation system for uncontrolled hypertension

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The U.S. Food and Drug Administration (FDA) has approved Recor Medical’s Paradise Ultrasound Renal Denervation (RDN) system for uncontrolled hypertension. The Recor system gained FDA clearance in November 2023.
The system, designed for patients with uncontrolled hypertension who are unresponsive to medication, uses ultrasound ablation to target nerves in the renal arteries, increasing blood flow. This approval comes just months after an FDA advisory panel voted in favor of the system. 
READ MORE >

American Heart Association ‘enthusiastically’ joins other cardiology groups in push for new, independent medical board

AHA members have voted to throw their full support behind the efforts to establish a new American Board of Cardiovascular Medicine. 

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doctor_patients.jpg
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American Heart Association ‘enthusiastically’ joins other cardiology groups in push for new, independent medical board

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doctor_patients.jpg
AHA members have voted to throw their full support behind the efforts to establish a new American Board of Cardiovascular Medicine. 
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In Other News

Philips inks 8-year partnership worth up to $115M with NYU Langone Health

As part of the deal, the top-ranked academic medical center will adopt Philips’ AI-powered imaging technologies, including handheld US. 

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NYU Langone Health
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Philips inks 8-year partnership worth up to $115M with NYU Langone Health

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NYU Langone Health
As part of the deal, the top-ranked academic medical center will adopt Philips’ AI-powered imaging technologies, including handheld US. 
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Company launches world's first online portal for MRI safety reporting

The web-based portal aims to log all accidents and any associated remedies, bringing as much information as possible to a central location.

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CAIRE-MRI Portal screenshot
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Company launches world's first online portal for MRI safety reporting

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CAIRE-MRI Portal screenshot
The web-based portal aims to log all accidents and any associated remedies, bringing as much information as possible to a central location.
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