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News You Need to Know Today
TAVR vs. SAVR after 5 years in low-risk patients | Semaglutide & PAD | Nasal spray not approved | GE HealthCare's new CT scanner
Monday, March 31, 2025
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Today's News and Trends

So far, so good: TAVR comparable to open heart surgery after 5 years in low-risk patients

Michael J. Reardon, MD, shared the highly anticipated data with a large audience at ACC.25 in Chicago. Overall, he said, these five-year findings suggest TAVR with a supra-annular, self-expanding valve is a safe and effective alternative to SAVR.

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Michael Reardon at ACC.25 presenting data on low-risk TAVR and SAVR patients
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So far, so good: TAVR comparable to open heart surgery after 5 years in low-risk patients

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Michael Reardon at ACC.25 presenting data on low-risk TAVR and SAVR patients
Michael J. Reardon, MD, shared the highly anticipated data with a large audience at ACC.25 in Chicago. Overall, he said, these five-year findings suggest TAVR with a supra-annular, self-expanding valve is a safe and effective alternative to SAVR.
READ MORE >

‘A practice-changing trial’: Semaglutide linked to key benefits for PAD patients with diabetes

Patients who present with type 2 diabetes and PAD often face substantial mobility issues. According to new data presented at ACC.25, however, treatment with semaglutide could represent a major step forward for this high-risk population.

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Semaglutide, the GLP-1 receptor agonist sold by Novo Nordisk under the brand names Wegovy and Ozempic, is associated with significant health benefits for patients with type 2 diabetes and peripheral artery disease (PAD), according to a late-breaking clinical trial presented at ACC.25, the annual meeting of the American College of Cardiology (ACC).
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‘A practice-changing trial’: Semaglutide linked to key benefits for PAD patients with diabetes

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Semaglutide, the GLP-1 receptor agonist sold by Novo Nordisk under the brand names Wegovy and Ozempic, is associated with significant health benefits for patients with type 2 diabetes and peripheral artery disease (PAD), according to a late-breaking clinical trial presented at ACC.25, the annual meeting of the American College of Cardiology (ACC).
Patients who present with type 2 diabetes and PAD often face substantial mobility issues. According to new data presented at ACC.25, however, treatment with semaglutide could represent a major step forward for this high-risk population.
READ MORE >

FDA chooses not to approve new nasal spray for heart rhythm issues

Etripamil's journey toward FDA approval hit a roadblock. The agency requested additional information on the drug, including a new facility inspection, in a response letter sent to Milestone Pharmaceuticals. 

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nasal_spray.jpg
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FDA chooses not to approve new nasal spray for heart rhythm issues

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nasal_spray.jpg
Etripamil's journey toward FDA approval hit a roadblock. The agency requested additional information on the drug, including a new facility inspection, in a response letter sent to Milestone Pharmaceuticals. 
READ MORE >

Oral semaglutide reduces heart risks while helping patients move past ‘fear of the needle’

Researchers still think patients should receive an injectable version of semaglutide when possible, but new data out of ACC.25 confirm that an oral formulation of the drug is associated with significant benefits.  

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Darren K. McGuire, MD, discusses late-breaking data on oral semaglutide
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Oral semaglutide reduces heart risks while helping patients move past ‘fear of the needle’

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Darren K. McGuire, MD, discusses late-breaking data on oral semaglutide
Researchers still think patients should receive an injectable version of semaglutide when possible, but new data out of ACC.25 confirm that an oral formulation of the drug is associated with significant benefits.  
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GE HealthCare launches new cardiac CT scanner with advanced AI capabilities

GE HealthCare designed the new-look Revolution Vibe CT scanner to help hospitals and health systems embrace CCTA and improve overall efficiency.

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GE HealthCare recently received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Revolution Vibe CT system, which the company said is squarely aimed at the rapidly growing coronary computed tomography angiography (CCTA) market.
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GE HealthCare launches new cardiac CT scanner with advanced AI capabilities

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GE HealthCare recently received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Revolution Vibe CT system, which the company said is squarely aimed at the rapidly growing coronary computed tomography angiography (CCTA) market.
GE HealthCare designed the new-look Revolution Vibe CT scanner to help hospitals and health systems embrace CCTA and improve overall efficiency.
READ MORE >

Featured Articles

ACC urges RFK Jr. to make Medicare reform a priority, warns against mass layoffs

The American College of Cardiology has sent a letter to HHS Secretary Robert F. Kennedy Jr. that outlines some of the organization’s central priorities and concerns. 

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healthcare policy reform government
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ACC urges RFK Jr. to make Medicare reform a priority, warns against mass layoffs

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healthcare policy reform government
The American College of Cardiology has sent a letter to HHS Secretary Robert F. Kennedy Jr. that outlines some of the organization’s central priorities and concerns. 
READ MORE >

Strokes more likely for U.S. heart transplant recipients following policy change

A nationwide policy shift implemented in 2018 was designed to, among other things, improve the waiting list mortality rate. One unintended consequence, however, is that patients are now more likely to experience a stroke after receiving a new heart.

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Heart cardiologists doctors surgery
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Strokes more likely for U.S. heart transplant recipients following policy change

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Heart cardiologists doctors surgery
A nationwide policy shift implemented in 2018 was designed to, among other things, improve the waiting list mortality rate. One unintended consequence, however, is that patients are now more likely to experience a stroke after receiving a new heart.
READ MORE >

Abbott gains CE mark approval for Volt PFA system

The approval, which Abbott said arrived earlier than expected, came after regulators reviewed data from a 2024 clinical trial.

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The Abbott Volt Pulsed Field Ablation catheter was cleared by the FDA in December 2025 and earlier had gained European CE mark.
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Abbott gains CE mark approval for Volt PFA system

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The Abbott Volt Pulsed Field Ablation catheter was cleared by the FDA in December 2025 and earlier had gained European CE mark.
The approval, which Abbott said arrived earlier than expected, came after regulators reviewed data from a 2024 clinical trial.
READ MORE >

In Case You Missed It

American College of Cardiology shares new guidance focused on evaluation, management of cardiogenic shock

The new document represents the ACC’s first Concise Clinical Guidance; it was designed to be an easy-to-use reference for keeping track of a complicated topic. 

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A majority of medical devices involved in Class I recalls were never required by the U.S. Food and Drug Administration (FDA) to undergo premarket or postmarket clinical testing, according to new research published in Annals of Internal Medicine.[1]
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American College of Cardiology shares new guidance focused on evaluation, management of cardiogenic shock

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A majority of medical devices involved in Class I recalls were never required by the U.S. Food and Drug Administration (FDA) to undergo premarket or postmarket clinical testing, according to new research published in Annals of Internal Medicine.[1]
The new document represents the ACC’s first Concise Clinical Guidance; it was designed to be an easy-to-use reference for keeping track of a complicated topic. 
READ MORE >

FDA clears first generic versions of rivaroxaban—what it means for patient care

Dave Dixon, PharmD, explored the short- and long-term impact of these approvals, noting that they could help reduce costs down the line.

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Video of Dave Dixon explaining the impact of first FDA approval of a generic DOAC.
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FDA clears first generic versions of rivaroxaban—what it means for patient care

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Video of Dave Dixon explaining the impact of first FDA approval of a generic DOAC.
Dave Dixon, PharmD, explored the short- and long-term impact of these approvals, noting that they could help reduce costs down the line.
READ MORE >

Bracco updates HeartSee coronary flow capacity software with new diagnostic features

Clinicians have been using HeartSee to diagnose and treat coronary artery disease since the technology first debuted back in 2018. These latest updates, set to roll out to existing users, are designed to improve diagnostic performance and user access.

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HeartSee 4.0 Bracco Diagnostics
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Bracco updates HeartSee coronary flow capacity software with new diagnostic features

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HeartSee 4.0 Bracco Diagnostics
Clinicians have been using HeartSee to diagnose and treat coronary artery disease since the technology first debuted back in 2018. These latest updates, set to roll out to existing users, are designed to improve diagnostic performance and user access.
READ MORE >

In Other News

300+ groups urge Senate GOP to reject Medicaid cuts

In an open letter, advocacy groups said the budget proposal passed by the U.S. House of Representatives would “shred our nation’s social safety net.”

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300+ groups urge Senate GOP to reject Medicaid cuts

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In an open letter, advocacy groups said the budget proposal passed by the U.S. House of Representatives would “shred our nation’s social safety net.”
READ MORE >

PET method offers new insight into inflammation of the brain

Researchers are hopeful that their technique could improve the diagnosis of conditions associated with neural inflammation. 

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brain.jpg
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PET method offers new insight into inflammation of the brain

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brain.jpg
Researchers are hopeful that their technique could improve the diagnosis of conditions associated with neural inflammation. 
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