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News You Need to Know Today
TAVR Highlights: A key PARTNER 3 update | Medtronic launches new guidewire | How to minimize bleeding risks | SGLT2 inhibitors
Wednesday, November 5, 2025
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Editor's Choice: TAVR

PARTNER 3 update: TAVR still comparable to SAVR in low-risk patients after 7 years

PARTNER 3 has been one of the most closely watched clinical trials in cardiology for many years now. Michael J. Mack, MD, presented a seven-year update during a packed session at TCT 2025. 

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Michael J. Mack, MD, discusses his team's seven-year update to the PARTNER 3 trial at TCT 2025 in San Francisco.
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PARTNER 3 update: TAVR still comparable to SAVR in low-risk patients after 7 years

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Michael J. Mack, MD, discusses his team's seven-year update to the PARTNER 3 trial at TCT 2025 in San Francisco.
PARTNER 3 has been one of the most closely watched clinical trials in cardiology for many years now. Michael J. Mack, MD, presented a seven-year update during a packed session at TCT 2025. 
READ MORE >

Medtronic launches FDA-cleared guidewire compatible with multiple TAVR systems

The guidewire was built specifically with Medtronic's own Evolut platform in mind. However, it is also compatible with all other commercially available TAVR systems.

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Medtronic Stedi Extra Support guidewire
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Medtronic launches FDA-cleared guidewire compatible with multiple TAVR systems

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Medtronic Stedi Extra Support guidewire
The guidewire was built specifically with Medtronic's own Evolut platform in mind. However, it is also compatible with all other commercially available TAVR systems.
READ MORE >

How to minimize bleeding risks after TAVR

Bleeding events remain a serious complication after TAVR. By identifying high-risk patients early and planning ahead, however, care teams can keep them to a minimum.

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A majority of medical devices involved in Class I recalls were never required by the U.S. Food and Drug Administration (FDA) to undergo premarket or postmarket clinical testing, according to new research published in Annals of Internal Medicine.[1]
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How to minimize bleeding risks after TAVR

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A majority of medical devices involved in Class I recalls were never required by the U.S. Food and Drug Administration (FDA) to undergo premarket or postmarket clinical testing, according to new research published in Annals of Internal Medicine.[1]
Bleeding events remain a serious complication after TAVR. By identifying high-risk patients early and planning ahead, however, care teams can keep them to a minimum.
READ MORE >

SGLT2 inhibitors after TAVR may boost survival, limit bioprosthetic valve dysfunction

Prescribing these drugs to TAVR patients could improve certain clinical outcomes, according to a new study of nearly 27,000 adults. 

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heart drugs with stethoscope
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SGLT2 inhibitors after TAVR may boost survival, limit bioprosthetic valve dysfunction

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heart drugs with stethoscope
Prescribing these drugs to TAVR patients could improve certain clinical outcomes, according to a new study of nearly 27,000 adults. 
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Medtronic announces new AI partnership focused on improving TAVR care

Participating TAVR programs will receive AI-powered recommendations courtesy of DASI Simulations.

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heart data AI algorithm cardiologist doctor
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Medtronic announces new AI partnership focused on improving TAVR care

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heart data AI algorithm cardiologist doctor
Participating TAVR programs will receive AI-powered recommendations courtesy of DASI Simulations.
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Performing PCI and TAVR together may improve in-hospital outcomes, long-term survival

When patients require PCI and TAVR, performing them at the same time is associated with both short- and long-term benefits. 

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A transcatheter aortic valve replacement (TAVR) procedure being performed at Intermountain Healthcare. Image from Intermountain Healthcare. Sex differences in TAVR one-year mortality.
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Performing PCI and TAVR together may improve in-hospital outcomes, long-term survival

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A transcatheter aortic valve replacement (TAVR) procedure being performed at Intermountain Healthcare. Image from Intermountain Healthcare. Sex differences in TAVR one-year mortality.
When patients require PCI and TAVR, performing them at the same time is associated with both short- and long-term benefits. 
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DAPT during valve-in-valve TAVR may reduce stroke risk—more data still required

New research suggests there may be a cardiovascular benefit to considering dual antiplatelet therapy for valve-in-valve TAVR patients.

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Pills
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DAPT during valve-in-valve TAVR may reduce stroke risk—more data still required

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Pills
New research suggests there may be a cardiovascular benefit to considering dual antiplatelet therapy for valve-in-valve TAVR patients.
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In Case You Missed It

Cardiologists, heart surgeons sound alarm over widespread use of TAVR in low-risk patients

Are too many low-risk patients with severe AS undergoing TAVR instead of SAVR? According to one group of clinicians, "a significant public health concern may be looming."

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cardiologist viewing heart data
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Cardiologists, heart surgeons sound alarm over widespread use of TAVR in low-risk patients

Share on Twitter Share on Facebook Share on Linkedin
cardiologist viewing heart data
Are too many low-risk patients with severe AS undergoing TAVR instead of SAVR? According to one group of clinicians, "a significant public health concern may be looming."
READ MORE >

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