CardioVascular Institute trial provides treatment for left-sided heart failure
HARRISBURG, Pa., July 15, 2014 /PRNewswire/ -- Following a heart attack, many heart failure patients suffer from enlargement of their left ventricle, diminishing the amount of blood the heart can pump to the body and resulting in life-threatening left-sided heart failure symptoms such as shortness of breath, decreased urine production, fatigue, and irregular or rapid heartbeat. Treatment options for patients whose left ventricle has enlarged have been limited, until now. Through a percutaneous (needle-puncture of the skin) procedure now available through a clinical trial at PinnacleHealth CardioVascular Institute the first minimally invasive catheter-based device aims to restore normal geometry and function in the damaged muscle (left ventricle). The device is called Parachute and is created by CardioKinetix in California.
The PARACHUTE IV clinical trial will enroll 560 patients with left ventricular (LV) systolic dysfunction in 80 hospitals across the country. The procedure, which takes approximately 75 minutes, is performed in a catheterization laboratory setting and patients are under conscious sedation (rather than general anesthesia). The Parachute implant partitions the damaged muscle, isolating the non-functional muscle segment from the functional segment.
Brijeshwar Maini, M.D., FACC, Director, Structural Heart and Advanced Cardiovascular Interventions at the PinnacleHealth CardioVascular Institute, serves as principal investigator for the PARACHUTE IV trial. "This unique device allows us to provide new options for our heart failure patients," said Dr. Maini. "We are fortunate to have access to this leading edge technology right here in Harrisburg."
"Access to the Parachute is another key milestone for heart failure patients in central Pennsylvania," said Phil Guarneschelli, Senior Vice President and Chief Operating Officer of PinnacleHealth. "Through PinnacleHealth CardioVascular Institute, our physicians continue to innovate care every day for our community. About PinnacleHealth SystemPinnacleHealth is a pioneer not-for-profit healthcare system dedicated to providing and improving the health and quality of life for the people of Central Pennsylvania since 1873. A proven leader in medical innovation, PinnacleHealth offers a wide range of services from primary care to the most complex surgeries and Magnet recognition for nursing excellence. The healthcare network includes four campuses (Community, West Shore, Harrisburg and Polyclinic) and medical services, including family practice, imaging, outpatient surgery and oncology, at multiple locations throughout the region.
About CardioKinetix
CardioKinetix, based in Menlo Park, Calif., is pioneering the catheter-based Parachute Ventricular Partitioning Device for heart failure. Privately held, the company is backed by SV Life Sciences, New Leaf Venture Partners, U.S. Venture Partners, Archer Ventures, Panorama Capital, H&Q Healthcare Investors and H&Q Life Sciences Investors.