Influence of Cardiac Arrest and Cardiogenic Shock on Outcomes in STEMI Patients

Minneapolis, MN – March 1, 2017 – The influence of cardiac arrest and cardiogenic shock on outcomes of patients with ST-elevation myocardial infarction (STEMI) has not been completely studied. Researchers at the Minneapolis Heart Institute Foundation® conducted a study to determine the incidence, characteristics and outcomes of STEMI complicated by cardiac arrest with or without cardiogenic shock. Prospective data from the Level I regional STEMI program at the Minneapolis Heart Institute® at Abbott Northwestern Hospital was examined from March 2003 to December 2014. Researchers analyzed STEMI patients who had cardiac arrest prior to any intervention. They specifically sought to determine how the type of cardiac arrest (shockable versus non-shockable rhythm) and the presence of cardiogenic shock affect patient outcomes. Researchers from the Minneapolis Heart Institute Foundation, led by Benjamin Johnson, MD, enrolled 4,511 patients in this study. The incidence of cardiac arrest prior to intervention was 11%. In-hospital death occurred in 250 (6%) of patients. Cardiac arrest was present in 56% and cardiogenic shock in 53% of these patients. In patients with shockable cardiac arrest, in-hospital mortality was 2.8x higher if they had cardiogenic shock as compared to no cardiogenic shock. In patients with non-shockable cardiac arrest, in-hospital mortality was equally high regardless of the presence of cardiogenic shock. Among this 4,511 patient cohort, cardiac arrest and/or cardiogenic shock accounted for 76% of all hospital deaths.  Benjamin Johnson, MD, principal investigator at the Minneapolis Heart Institute Foundation notes, “Cardiac arrest and cardiogenic shock are associated with significantly increased morbidity and mortality in patients presenting with ST elevation myocardial infarction (STEMI). Efforts need to be made to better understand this population of patients presenting with STEMI complicated by cardiac arrest with or without cardiogenic shock.” The researchers will present the results of that study at the American College of Cardiology Annual Scientific Session & Expo this month. About the Minneapolis Heart Institute Foundation®The Minneapolis Heart Institute Foundation (MHIF) strives to create a world without heart and vascular disease. To achieve this bold vision, it is dedicated to improving the cardiovascular health of individuals and communities through innovative research and education.

• Scientific Innovation and Research — MHIF is a recognized research leader in the broadest range of cardiovascular medicine and population health initiatives. Each year MHIF leads more than 175 active research projects and publishes more than 175 peer-reviewed abstracts. Cardiologists, hospitals and communities around the world adopt MHIF protocols to save lives, improve care and create healthier living opportunities.
• Education and Outreach — MHIF provides more than 10,000 hours of education each year putting its research into practice to improve outcomes. And, MHIF leads cutting-edge, transformative population health research to connect, engage, inform and empower individuals and communities to improve their health.

The Minneapolis Heart Institute Foundation’s work is funded by generous donors and sponsors and supports research initiatives of Minneapolis Heart Institute® at Abbott Northwestern Hospital.
Minneapolis Heart Institute® physicians provide care for patients at Abbott Northwestern Hospital in Minneapolis and at 38 community sites across Minnesota and western Wisconsin.