Heart Rhythm

Hearts should have normal rhythm to their beats, but when these beats are out of synch, it causes inefficient pumping of blood. Irregular heart arrhythmias occur when the electrical signals that coordinate the heart's beats do not work properly. This can cause beats that are too fast (tachycardia), or too slow (bradycardia). Tachycardias include atrial fibrillation (AFib), supraventricular tachycardia, ventricular fibrillation, and ventricular tachycardia (VT). Bradycardias include sick sinus syndrome and conduction block. Electrophysiology arrhythmia treatments include medications, life style changes, and the EP lab interventions of catheter ablation, and implantable pacemakers or defibrillators.

Medtronic announces CE mark and European launch of TYRX(TM) Absorbable Antibacterial Envelope

Medtronic, Inc. has received CE (Conformité Européenne) Mark for the TYRX(TM) Absorbable Antibacterial Envelope. This innovative mesh envelope covers an implantable cardiac device to help stabilize the device after implantation and reduce surgical-site infections.

The importance of keeping afib warfarin control stable

Steady time in therapeutic range is important for optimal care when treating atrial fibrillation patients using warfarin. However, research published online Sept. 2 in Circulation: Cardiovascular Quality and Outcomes insists that stability, seen through the international normalized ratio, not be overlooked.

When measuring novel anticoagulants, proceed with caution

The beauty of novel oral anticoagulants is that they come in fixed doses and don’t require monitoring, as warfarin does. Still, some circumstances warrant an assay, and clinicians should be aware of the potential pitfalls.

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Afib patients living longer with ablation-maintained sinus rhythm

Can a little heat really mend a broken heart? Patients with atrial fibrillation were found to have a better mortality rate when sinus rhythm was maintained through radiofrequency ablation (RFA) according to a study published in the September issue of Heart Rhythm.

Get With The Guidelines' newest kid on the block: Afib

The American Heart Association has made improvements to guideline adherence in the treatment of atrial fibrillation a priority, according to a paper published Sept. 2 in Circulation: Cardiovascular Quality and Outcomes.

ESC Hot Line: Data reports NVAF patients taking Pradaxa (dabigatran etexilate mesylate) experienced slower decline in kidney function compared to those on warfarin

Boehringer Ingelheim Pharmaceuticals, Inc. today announced results from a new post-hoc sub-analysis of the pivotal phase III RE-LY trial assessing renal function change in patients with non-valvular atrial fibrillation (NVAF) treated with Pradaxa (dabigatran etexilate mesylate) compared to warfarin. The findings suggest that patients treated with PRADAXA experienced a slower decline in kidney function compared to those being treated with warfarin, with the slower decline most marked in patients treated with PRADAXA who had mild kidney impairment at the start of the RE-LY trial. The results were presented today during the European Society of Cardiology (ESC) Congress 2014.

Global survey of cardiologists highlights complexity of managing non-valvular atrial fibrillation and reinforces need for individualized approach to patient care

Daiichi Sankyo and the Heart Rhythm Society today announced results from a global survey, which polled cardiologists from around the world and revealed that a majority (58%) of cardiologists agree that there is no such thing as a “typical” non-valvular atrial fibrillation (NVAF) patient.

Subgroup analysis of ENGAGE AF-TIMI 48 explores the relationship between edoxaban dose, concentration, anti-Factor Xa activity and outcomes

Daiichi Sankyo Company, Limited today announced data from a subgroup analysis of the phase 3 ENGAGE AF-TIMI 48 study, that explores the relationship between edoxaban dose, concentration and anti-factor Xa activity in patients with non-valvular atrial fibrillation (NVAF). The analysis also compared rates of major bleeding and efficacy outcomes [stroke and systemic embolic events (SEE)] of edoxaban versus warfarin, stratified by dose reduction status.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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