Interventional Cardiology

This cardiac subspecialty uses minimally invasive, catheter-based technologies in a cath lab to diagnose and treat coronary artery disease (CAD). The main focus in on percutaneous coronary interventions (PCI) to revascularize patients with CAD that is causing blockages resulting in ischemia or myocardial infarction. PCI mainly consists of angioplasty and implanting stents. Interventional cardiology has greatly expanded in scope over recent years to include a number of transcatheter structural heart interventions.

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TCT: No additional risk of bleeding with DES use in octogenarians

MIAMI—The results of a study with a cohort of octogenarians with severe coronary artery disease found that the patients responded well to treatment with drug-eluting stents (DES) with no increase in bleeding compared to bare metal stents.

TCT: Smooth operators: High-volume = good outcomes for radial STEMI

MIAMI—In STEMI patients presenting within 12 hours of symptom onset, the radial approach was associated with a significant lower incidence of major bleeding and access site complications and a significant better net clinical benefit, according to the late-breaking STEMI RADIAL trial, presented Oct. 26 at the annual Transcatheter Cardiovascular Therapeutics (TCT) conference.

Pediatric oxygenation system cleared for use in U.S.

The FDA has granted Medtronic 510(k) clearance for its Affinity Pixie oxygenation system.

TCT: Personalized hydration strategies significantly reduce contrast-induced nephropathy

MIAMI—A personally tailored hydration regimen can significantly reduce the incidence of kidney injury in patients at risk of contrast-induced nephropathy undergoing coronary angiography, researchers reported Oct. 25 at the Transcatheter Cardiovascular Therapeutics (TCT) conference.

TCT: Newer DES effective in treating unprotected left main artery disease

MIAMI—Second-generation drug-eluting stents are feasible and effective in the treatment of unprotected left main coronary artery lesions, according to findings presented Oct. 24 at the late-breaking trials at the Transcatheter Cardiovascular Therapeutics conference.

TCT: After angio confirms ACS, should more potent antiplatelets be considered?

MIAMI—Physicians should weigh the benefits and risks of more intensive antiplatelet therapy for patients in whom angiography is performed and coronary disease is confirmed, whether the patient receives medical therapy or PCI, according to the lead investigator of the late-breaking TRILOGY ACS trial presented Oct. 24 at the Transcatheter Cardiovascular Therapeutics (TCT) conference. However, because the overall TRILOGY trial was negative, the results of the trial are only hypothesis generating.

TCT: 1-year results favorable for 38 mm stent

The 38 mm Resolute drug-eluting stent met its performance goal with a one-year target lesion failure (TLF) rate of 5.4 percent for patients being treated for long coronary artery lesions, according to findings presented Oct. 23 at the 2012 Transcatheter Cardiovascular Therapeutics conference in Miami. The TLF rate among diabetic patients was similar.

TCT: Platelet reactivity monitoring bests standard prasugrel Rx for bleeds, thrombotic events

MIAMI—Platelet reactivity monitoring is superior to a one-dose-fits-all strategy with prasugrel in reducing the rate of both high and low on-treatment platelet reactivity, which in turn impacts the adverse event rates in those patients, according to a study presented Oct. 22 at the 2012 Transcatheter Cardiovascular Therapeutics (TCT) conference.

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