Pulmonary embolism

Pulmonary embolism (PE) is the third leading cardiovascular cause of death after heart attacks and stroke. PE is caused by blood clots in the pulmonary arteries. These are often caused by clots from the venous system, including thrombus from trauma, surgery or deep vein thrombosis (DVT). Treatment has traditionally been systemic use of thrombolytic drugs to dissolve the clot. But in cases there is a massive, life-threatening PE, or chronic clot burden that have remained in a vessel for an extended period of time, mechanical thrombectomy and ultrasound-assisted catheter-directed thrombolysis (USCDT) is being used as more targeted and aggressive treatments.

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Medical device startup exits stealth mode to name CEO, announce $21M in funding

Jupiter Endovascular, a new subsidiary of Neptune Medical, aims to "bring the precision and control of direct surgical access to catheter-based interventions.”  

Sahil Parikh, MD, FSCAI, Director of Endovascular Services at New York-Presbyterian Columbia University Irving Medical Center, and Associate Professor of Medicine at the Columbia University College of Physicians and Surgeons, explains there is scant clinical data on what the standard of care should be for pulmonary embolism, so it is up to clinicians to decide what is best for patients based on whether patients have mild to severe PE.

Pulmonary embolism treatments continue to evolve

There is still a lack of lack of standardized treatment protocols for pulmonary embolism. This is mainly due to limited data and a lack of reliable risk assessments, one specialist explained.

Video interview with Sahil Parikh, MD, FSCAI, director of endovascular services, New York-Presbyterian Columbia University Irving Medical Center and associate professor of medicine at Columbia University, who discusses the disparities in PE treatments in the REAL-PE study

REAL-PE highlights disparities in pulmonary embolism care

Sahil Parikh, MD, director of endovascular services, New York-Presbyterian, explains details from the big-data REAL-PE study comparing mechanical thrombectomy to ultrasound assisted catheter thrombolysis.

Video interview with Peter Monteleone, MD, explaining the primary catheter-based interventional tools used to treat pulmonary embolism (PE).

A cardiologist's guide to treating pulmonary embolism

Interventional cardiologist Peter Monteleone, MD, discussed the primary tools used to treat pulmonary embolism in the cath lab.

Video of Peter Monteleone, MD, discusses role of cardiology in pulmonary embolism response teams (PERT). CT image of the heart showing bilateral pulmonary embolism blood clots in the pulmonary arteries leading into the lungs.

Interventional cardiology sees growing role in pulmonary embolism interventions

Peter Monteleone, MD, national director of cardiovascular research at Ascension Health, explains the growing role of interventional cardiology in pulmonary embolism treatment and PERT teams.

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AI dramatically reduces radiologists’ rate of missed incidental pulmonary embolism on routine CT

The commercial software also reduced the median detection and notification time for incidental PE in flagged scans from “several days” down to just 1 hour.

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Why more pulmonary embolism patients should be considered for surgery

The topic was explored at length in a new scientific statement presented at the 59th Annual Meeting of the Society of Thoracic Surgeons.

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Catheter-directed thrombolysis boosts survival rates for submassive pulmonary embolism

The new meta-analysis included data from nearly 10,000 patients. 

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.