Bicuspid aortic valve repair leads to 'excellent' long-term outcomes

Patient survival after bicuspid aortic valve (BAV) repair, with our without concomitant aortic replacement, is “excellent,” according to a new analysis published in JAMA Cardiology.

The study’s authors tracked more than 1,000 patients who underwent BAV repair for aortic regurgitation and/or ascending aortic aneurysm from October 1995 to June 2018. All patients were treated at the same institution, and the mean patient follow-up was 56 months.

In the study, the researchers detailed how they shifted their policies over the years to improve patient care. They “identified important factors associated with valve failure” and worked to address each issue. For example, after noting that symmetric prolapse was “an important mode of failure,” the team employed an effective height concept when selecting valves for repair. Another ongoing issue was the use of autologous pericardium as partial cusp replacement.

“These results led us to modify our repair approach by selecting patients more carefully,” wrote lead author Ulrich Schneider, MD, Saarland University Medical Center in Germany, and colleagues. “More important, we developed a suture annuloplasty to address annular dilatation, with good midterm results. We also modified the circumferential orientation, attempting to come as close as possible to a symmetric configuration.”