Vascular & Endovascular

This channel includes news on non-coronary vascular disease and therapies. These include peripheral artery disease (PAD), abdominal and thoracic aortic aneurysm (AAA and TAA), aortic dissection, pulmonary embolism (PE), critical limb ischemia (CLI), carotid artery and stroke interventions, venous interventions, deep vein thrombosis (DVT), and interventional radiology therapies. The focus on most of these therapies is minimally invasive, catheter-based procedures performed in a cath lab.

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Revised guidelines help reduce risk of recurrent strokes

Revised guidelines for the prevention of future stroke for survivors of a stroke or transient ischemic attack (TIA) align with other guidelines and provide additional sections based on new insights on risk factors.

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Renal Denervation: Beginning of the End or End of the Beginning?

When Medtronic announced in January that SYMPLICITY HTN-3 failed to meet its efficacy endpoint, it sounded like the beginning of the end for renal denervation as a treatment for uncontrolled hypertension.

ZZ Biotech announces phase 2 trial with 3K3A-APC in stroke; funds will be provided by NIH and Broadview Ventures

ZZ Biotech today announced that the National Institutes of Health will support a multicenter Phase 2 clinical trial of its experimental drug, 3K3A-APC, in patients suffering from acute ischemic stroke.

Target: Stroke hits a bull’s eye with timely care, improved outcomes

A pre-post analysis of a national stroke initiative found patients were more likely to receive timely treatment and have better outcomes after the launch of the quality improvement program. The results were published in the April 23/30 issue of JAMA.

New clinical data from PANDORA and ENGAGE affirm market-leading medical device’s durable, consistent and proven outcomes In endovascular treatment of abdominal aortic aneurysms

The Endurant AAA stent graft system from Medtronic, Inc. continues to demonstrate exceptional long-term performance in the endovascular treatment of abdominal aortic aneurysms, according to new clinical data presented for the first time at the 2014 Charing Cross international symposium in London.

Head-to-head study reports patient comfort With Visipaque (iodixanol) and Isovue (iopamidol) during peripheral arteriography

GE Healthcare today announced results from a new study, which showed that patients receiving Visipaque(tm) (iodixanol) 320mg I/ml reported less discomfort, characterized by heat or cold sensation or pain upon injection, than patients receiving Isovue(r) (iopamidol) 370 mg I/ml during peripheral arteriography. As with other iodinated contrast agents, Visipaque is often associated with sensations of discomfort, warmth or pain. The data were presented at the American College of Cardiology's 63rd Annual Scientific Session and Expo.

Covidien recalls embolization, retrieval devices

Covidien is recalling some endovascular devices due to a coating defect.

Europeans call for trials akin to caliber of HTN-3

The European Society of Hypertension (ESH) is calling for rigorous trials on renal denervation as a therapy for patients with treatment-resistant hypertension in the wake of results presented in the failed SYMPLICITY HTN-3 clinical trial.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.