Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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Higher doses of rivaroxaban linked to increased risk of brain bleeds

Normal daily doses of rivaroxaban (15 to 20 mg) are linked to triple the risk of intracerebral hemorrhage (ICH) when compared to aspirin, according to a meta-analysis of five randomized trials published Aug. 13 in JAMA Neurology.

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Stroke deaths decline in Europe—but improvement is needed

New research published in the European Heart Journal highlights how overall cerebrovascular disease deaths in Europe have declined. But that improvement has leveled off in some EU countries.

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How deadly is Takotsubo syndrome? It depends on the trigger

Originally thought to be a benign condition, Takotsubo syndrome is associated with long-term outcomes similar to acute coronary syndrome (ACS), researchers reported in the Journal of the American College of Cardiology. And in cases where Takotsubo syndrome (TTS) is triggered by physical events, prognosis is even worse.

Pill combining 3 medications boosts BP control

Patients who were prescribed a single pill with low doses of three antihypertensive medications reached their blood pressure (BP) targets more often than those following a usual care plan, according to a randomized trial of 700 individuals from the Sri Lankan public health system.

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CLI revascularization techniques are more cost-effective, associated with longer survival than amputation

Revascularization techniques to treat primary critical limb ischemia (CLI) may be more cost-effective and associated with longer survival than primary major amputation, according to new research published in the Journal of the American Heart Association.

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‘Miraculous’ gene therapies may offer one-time cure for hemophilia

Experimental gene therapies to treat hemophilia are still undergoing testing, but early results from clinical trials have both researchers and patients optimistic the condition can be cured once and for all.

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Higher BMI increases risk for peripheral artery disease, critical limb ischemia

Maintaining an optimal body mass index (BMI), in addition to controlling other cardiovascular risk factors, may reduce the risk of peripheral artery disease (PAD) with critical limb ischemia (CLI), according to new research in the Journal of the American Heart Association.

Edoxaban tops warfarin in study of Asian patients with AFib

The factor Xa inhibitor edoxaban might reduce the risk of several adverse events—including stroke, major bleeding and all-cause death—when compared to warfarin, according to a real-world study of Korean patients with atrial fibrillation (AFib).

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.