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A new use for IVL | TAVR & SAVR in patients with low-flow, low-gradient AS | Obicetrapib linked to substantial LDL-C reductions

News You Need to Know Today
A new use for IVL | TAVR & SAVR in patients with low-flow, low-gradient AS | Obicetrapib linked to substantial LDL-C reductions
Monday, May 12, 2025
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Today's News and Trends

A new use for IVL: helping cardiologists secure transcarotid access for TAVR

IVL can do more than help prep patients for PCI. In fact, one heart team used Shockwave Medical's IVL technology to secure access for a high-risk TAVR patient.

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Intravascular lithotripsy IVL carotid artery TAVR. (A) Invasive angiography of the right common carotid artery. (B) Invasive angiography of the brachiocephalic artery (note the heavily calcified aortic arch). (C and D) Intravascular lithotripsy (IVL) treatment of the brachiocephalic artery to the mid common carotid artery using a 7.0 × 60 mm × 135 cm Shockwave IVL balloon. (E) Successful deployment of a 23 mm SAPIEN 3 Ultra 9750 TFX Aortic Valve. Images courtesy of JACC: Case Reports
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A new use for IVL: helping cardiologists secure transcarotid access for TAVR

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Intravascular lithotripsy IVL carotid artery TAVR. (A) Invasive angiography of the right common carotid artery. (B) Invasive angiography of the brachiocephalic artery (note the heavily calcified aortic arch). (C and D) Intravascular lithotripsy (IVL) treatment of the brachiocephalic artery to the mid common carotid artery using a 7.0 × 60 mm × 135 cm Shockwave IVL balloon. (E) Successful deployment of a 23 mm SAPIEN 3 Ultra 9750 TFX Aortic Valve. Images courtesy of JACC: Case Reports
IVL can do more than help prep patients for PCI. In fact, one heart team used Shockwave Medical's IVL technology to secure access for a high-risk TAVR patient.
READ MORE >

TAVR and SAVR deliver similar outcomes for patients with low-flow, low-gradient aortic stenosis

Paravalvular leak was more common after TAVR, as one may expect, but that was the only notable difference between the two aortic valve replacement strategies. The study's authors did highlight the importance of additional research, including larger studies with longer follow-up periods.

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Doctor patient
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TAVR and SAVR deliver similar outcomes for patients with low-flow, low-gradient aortic stenosis

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Doctor patient
Paravalvular leak was more common after TAVR, as one may expect, but that was the only notable difference between the two aortic valve replacement strategies. The study's authors did highlight the importance of additional research, including larger studies with longer follow-up periods.
READ MORE >

Obicetrapib linked to substantial reductions in LDL cholesterol for high-risk heart patients

Researchers shared new studies on the highly selective CETP inhibitor in The New England Journal of Medicine and The Lancet.

READ MORE >
Cardiologist heart
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Obicetrapib linked to substantial reductions in LDL cholesterol for high-risk heart patients

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Cardiologist heart
Researchers shared new studies on the highly selective CETP inhibitor in The New England Journal of Medicine and The Lancet.
READ MORE >

Featured Articles

Cardiologists are first in world to use new cooling device to terminate AFib during surgery

Patients often develop AFib during cardiac surgery, leading to longer hospital stays, additional healthcare costs and a higher risk of mortality. Cooling the oblique sinus of the patient's heart as soon as AFib starts to develop may represent a new way to stop the problem in its tracks. 

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heart ice cool cold freezing frozen
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Cardiologists are first in world to use new cooling device to terminate AFib during surgery

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heart ice cool cold freezing frozen
Patients often develop AFib during cardiac surgery, leading to longer hospital stays, additional healthcare costs and a higher risk of mortality. Cooling the oblique sinus of the patient's heart as soon as AFib starts to develop may represent a new way to stop the problem in its tracks. 
READ MORE >

CCTA shows colchicine's impact on atherosclerosis progression

Matthew Budoff, MD, detailed new data highlighting CCTA's value when it comes to tracking the progression of coronary atherosclerosis.

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Matthew Budoff explains use of CCTA to track coronary disease plaque progression
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CCTA shows colchicine's impact on atherosclerosis progression

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Matthew Budoff explains use of CCTA to track coronary disease plaque progression
Matthew Budoff, MD, detailed new data highlighting CCTA's value when it comes to tracking the progression of coronary atherosclerosis.
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Rates of obesity, high blood pressure and diabetes keep climbing in US

As time goes on, the gaps between the healthiest states and the least healthy states are only getting wider and wider. "Our findings highlight the urgent need for targeted strategies to reduce state-based inequities in cardiometabolic risk factors,” researchers wrote. 

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Rates of obesity, high blood pressure and diabetes keep climbing in US

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As time goes on, the gaps between the healthiest states and the least healthy states are only getting wider and wider. "Our findings highlight the urgent need for targeted strategies to reduce state-based inequities in cardiometabolic risk factors,” researchers wrote. 
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AI-enabled CCTA evaluations reduce use of invasive imaging exams

This two-year analysis of the FISH&CHIPS study found that using advanced AI from Heartflow to evaluate cardiac CT is safe, effective and limits the use of unnecessary follow-up tests.

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An example of HeartFlow's FFR-CT technology, which takes the cardiac CT dataset and uses computational fluid dynamics to create virtual fraction flow reserve values. The FFR measurement can help determine if a coronary lesion is significant enough to require revascularization, or if the patient should be treated with medication. FFR-CT was included as a recommendation in select patients in the 2021 Chest Pain Guidelines.
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AI-enabled CCTA evaluations reduce use of invasive imaging exams

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An example of HeartFlow's FFR-CT technology, which takes the cardiac CT dataset and uses computational fluid dynamics to create virtual fraction flow reserve values. The FFR measurement can help determine if a coronary lesion is significant enough to require revascularization, or if the patient should be treated with medication. FFR-CT was included as a recommendation in select patients in the 2021 Chest Pain Guidelines.
This two-year analysis of the FISH&CHIPS study found that using advanced AI from Heartflow to evaluate cardiac CT is safe, effective and limits the use of unnecessary follow-up tests.
READ MORE >

In Case You Missed It

FDA announces new recall of Abbott heart pump accessories over significant safety risks

The mobile power units of certain HeartMate 3 and HeartMate II LVADs have been experiencing “sudden, unexpected performance issues” such as turning on, off or even restarting with no warning. These issues can potentially be fatal, according to an alert shared by the FDA.

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Product Recall
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FDA announces new recall of Abbott heart pump accessories over significant safety risks

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Product Recall
The mobile power units of certain HeartMate 3 and HeartMate II LVADs have been experiencing “sudden, unexpected performance issues” such as turning on, off or even restarting with no warning. These issues can potentially be fatal, according to an alert shared by the FDA.
READ MORE >

PFA startup founded by industry veteran to share first-in-human data at Heart Rhythm 2025

Field Medical, founded in 2022 by Steven Mickelsen, MD, is set to make a significant splash at the Heart Rhythm Society's annual meeting in San Diego. The company also just raised $40 million in financing.

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Field Medical's FieldForce pulsed field ablation system. Image courtesy of Field Medical.
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PFA startup founded by industry veteran to share first-in-human data at Heart Rhythm 2025

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Field Medical's FieldForce pulsed field ablation system. Image courtesy of Field Medical.
Field Medical, founded in 2022 by Steven Mickelsen, MD, is set to make a significant splash at the Heart Rhythm Society's annual meeting in San Diego. The company also just raised $40 million in financing.
READ MORE >

Same-day discharge after cardiac ablation: Cardiologists share recommendations

Same-day discharge won't always be a great fit after cardiac ablation, of course, but it has been associated with considerable patient satisfaction as well as improved efficiency and substantial cost savings. The Heart Rhythm Society and American College of Cardiology have shared a new scientific statement on the subject. 

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doctor patient discharge after heart surgery
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Same-day discharge after cardiac ablation: Cardiologists share recommendations

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doctor patient discharge after heart surgery
Same-day discharge won't always be a great fit after cardiac ablation, of course, but it has been associated with considerable patient satisfaction as well as improved efficiency and substantial cost savings. The Heart Rhythm Society and American College of Cardiology have shared a new scientific statement on the subject. 
READ MORE >

In Other News

U.S. iodine contrast supply may not be subject to proposed 25% tariffs

If President Trump initiates a 25% tariff against pharmaceuticals imported from Ireland, it might impact the price for X-ray iodine contrast agents in the U.S. depending what rules are put in place.

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Lawyer dies after severe allergic reaction to contrast media.
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U.S. iodine contrast supply may not be subject to proposed 25% tariffs

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Lawyer dies after severe allergic reaction to contrast media.
If President Trump initiates a 25% tariff against pharmaceuticals imported from Ireland, it might impact the price for X-ray iodine contrast agents in the U.S. depending what rules are put in place.
READ MORE >

FDA rolls out AI across all departments, hires new leadership

The agency said all of its centers will be fully integrated by June 30, following the success of an early pilot where generative AI supported scientific reviews. 

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U.S. FDA Sign
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FDA rolls out AI across all departments, hires new leadership

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U.S. FDA Sign
The agency said all of its centers will be fully integrated by June 30, following the success of an early pilot where generative AI supported scientific reviews. 
READ MORE >

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