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News You Need to Know Today
Popular obesity drugs & PAD | TTVR linked to positive real-world outcomes | New report raises questions about FDA, AstraZeneca
Thursday, June 26, 2025
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Today's News and Trends

Popular obesity drugs limit amputations, heart issues among patients with peripheral artery disease

Semaglutide, tirzepatide and other GLP-1 drugs appear to provide significant value for patients with moderate PAD.

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Semaglutide (Wegovy) injector pen. Photo by Dave Fornell
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Popular obesity drugs limit amputations, heart issues among patients with peripheral artery disease

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Semaglutide (Wegovy) injector pen. Photo by Dave Fornell
Semaglutide, tirzepatide and other GLP-1 drugs appear to provide significant value for patients with moderate PAD.
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TTVR with Evoque system linked to positive real-world outcomes after 30 days

According to early real-world data, the FDA-approved Evoque TTVR device is associated with positive outcomes when used to treat severe tricuspid regurgitation. 

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The Evoque transcatheter tricuspid valve replacement (TTVR) system for tricuspid regurgitation from Edwards Lifesciences. The Evoque is the first transcatheter tricuspid valve approved by the FDA. It is the first TTVR cleared in the U.S.
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TTVR with Evoque system linked to positive real-world outcomes after 30 days

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The Evoque transcatheter tricuspid valve replacement (TTVR) system for tricuspid regurgitation from Edwards Lifesciences. The Evoque is the first transcatheter tricuspid valve approved by the FDA. It is the first TTVR cleared in the U.S.
According to early real-world data, the FDA-approved Evoque TTVR device is associated with positive outcomes when used to treat severe tricuspid regurgitation. 
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New report raises questions about data that helped heart drug gain FDA approval

Ticagrelor, an antiplatelet medication from AstraZeneca commonly prescribed by cardiologists, gained FDA approval back in 2011. The author of a new investigative report, however, is raising several concerns about the data used to secure that approval.

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pharmaceutical drug approval process
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New report raises questions about data that helped heart drug gain FDA approval

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pharmaceutical drug approval process
Ticagrelor, an antiplatelet medication from AstraZeneca commonly prescribed by cardiologists, gained FDA approval back in 2011. The author of a new investigative report, however, is raising several concerns about the data used to secure that approval.
READ MORE >

Featured Articles

A closer look at world’s first TAVR patient treated with new cerebral embolic protection device

The device covers three vessels at once and can be deployed through the patient's TAVR access site. Researchers shared their first-in-human experience in JACC: Case Reports.

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EnCompass F2 device from Nevada-based EnCompass Technologies. (A) Aortic arch deflector composed of a cylindrical nitinol frame that covers all three vessels supplying blood flow to the brain while allowing passage of the transcatheter aortic valve replacement system through its center. (B) It features an electrospun filter with very small pore size (30 μm average). Images/caption courtesy of JACC: Case Reports and George et al.
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A closer look at world’s first TAVR patient treated with new cerebral embolic protection device

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EnCompass F2 device from Nevada-based EnCompass Technologies. (A) Aortic arch deflector composed of a cylindrical nitinol frame that covers all three vessels supplying blood flow to the brain while allowing passage of the transcatheter aortic valve replacement system through its center. (B) It features an electrospun filter with very small pore size (30 μm average). Images/caption courtesy of JACC: Case Reports and George et al.
The device covers three vessels at once and can be deployed through the patient's TAVR access site. Researchers shared their first-in-human experience in JACC: Case Reports.
READ MORE >

Surgeons complete first fully robotic heart transplant in US history

The historic procedure was performed in Texas on a 45-year-old patient who had been hospitalized for months with advanced heart failure.

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heart surgery Baylor St. Luke's Medical Center
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Surgeons complete first fully robotic heart transplant in US history

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heart surgery Baylor St. Luke's Medical Center
The historic procedure was performed in Texas on a 45-year-old patient who had been hospitalized for months with advanced heart failure.
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Society of Thoracic Surgeons provides on-the-go risk evaluations with new mobile app

The STS Risk Calculator App, available on both iOS and Android devices, gives users improved access to real-time risk assessments.

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physician acceptance of generative AI
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Society of Thoracic Surgeons provides on-the-go risk evaluations with new mobile app

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physician acceptance of generative AI
The STS Risk Calculator App, available on both iOS and Android devices, gives users improved access to real-time risk assessments.
READ MORE >

Heart Failure Society of America names its newest leaders and board members

Kenneth Margulies, MD, will be the group's next president. These new terms all begin after the HFSA Annual Scientific Meeting in September.

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 The Heart Failure Society of America (HFSA) recently announced its new officers and board members. Their terms start at the conclusion of the HFSA Annual Scientific Meeting 2025 (ASM) Sept. 26-29, 2025 in Minneapolis.
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Heart Failure Society of America names its newest leaders and board members

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 The Heart Failure Society of America (HFSA) recently announced its new officers and board members. Their terms start at the conclusion of the HFSA Annual Scientific Meeting 2025 (ASM) Sept. 26-29, 2025 in Minneapolis.
Kenneth Margulies, MD, will be the group's next president. These new terms all begin after the HFSA Annual Scientific Meeting in September.
READ MORE >

In Case You Missed It

FDA approves 3-in-1 polypill for hypertension

Widaplik, the new polypill from George Medicines, includes telmisartan, amlodipine and indapamide. The FDA's decision comes after positive data were published in both JACC and The Lancet.

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cardiologist doctor physician patient black diverse hypertension
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FDA approves 3-in-1 polypill for hypertension

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cardiologist doctor physician patient black diverse hypertension
Widaplik, the new polypill from George Medicines, includes telmisartan, amlodipine and indapamide. The FDA's decision comes after positive data were published in both JACC and The Lancet.
READ MORE >

Inspired by astronauts, researchers use high-tech pants to uncover heart issues on MRI

New first-in-human data highlight the potential of pants designed to improve the quality of MRI-based cardiac stress tests.

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Michael Nelson, associate professor, wears the lower body negative-pressure pants at UTA's Clinical Imaging Research Center / Image courtesy of UTA.
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Inspired by astronauts, researchers use high-tech pants to uncover heart issues on MRI

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Michael Nelson, associate professor, wears the lower body negative-pressure pants at UTA's Clinical Imaging Research Center / Image courtesy of UTA.
New first-in-human data highlight the potential of pants designed to improve the quality of MRI-based cardiac stress tests.
READ MORE >

Balloon-expandable, self-expanding TAVR valves associated with comparable long-term outcomes

Patients treated with the Sapien 3 platform from Edwards Lifesciences and the Evolut platform from Medtronic were linked to more similarities than differences after six years. This was a single-center study, researchers noted, but it does provide an in-depth look at the safety and effectiveness of TAVR.

READ MORE >
cardiologists heart doctors heart research heart data
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Balloon-expandable, self-expanding TAVR valves associated with comparable long-term outcomes

Share on Twitter Share on Facebook Share on Linkedin
cardiologists heart doctors heart research heart data
Patients treated with the Sapien 3 platform from Edwards Lifesciences and the Evolut platform from Medtronic were linked to more similarities than differences after six years. This was a single-center study, researchers noted, but it does provide an in-depth look at the safety and effectiveness of TAVR.
READ MORE >

In Other News

Healthcare AI today: Bipartisan AI policy guidance, AI claims denials, LLM brain rot, more

Federal lawmakers have a fresh resource to keep them up on healthcare AI that falls outside of formal FDA oversight. It comes in the form of a new report from the nonprofit Bipartisan Policy Center.

READ MORE >
artificial intelligence AI explainable ethical responsible
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Healthcare AI today: Bipartisan AI policy guidance, AI claims denials, LLM brain rot, more

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artificial intelligence AI explainable ethical responsible
Federal lawmakers have a fresh resource to keep them up on healthcare AI that falls outside of formal FDA oversight. It comes in the form of a new report from the nonprofit Bipartisan Policy Center.
READ MORE >

Why do AI-savvy consumers harbor skepticism toward medical AI?

Patients who frequently use AI tend to readily trust AI-assisted diagnoses made by their physicians. Counterintuitively, however, those who would rank themselves among the very best-informed about AI tend to mistrust such diagnoses. 

READ MORE >
gamer skeptical about medical AI
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Why do AI-savvy consumers harbor skepticism toward medical AI?

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gamer skeptical about medical AI
Patients who frequently use AI tend to readily trust AI-assisted diagnoses made by their physicians. Counterintuitively, however, those who would rank themselves among the very best-informed about AI tend to mistrust such diagnoses. 
READ MORE >

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