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CABG or PCI? | New drug candidate for AFib fails | Leadership changes at Edwards Lifesciences | Drinking habits & heart health

News You Need to Know Today
CABG or PCI? | New drug candidate for AFib fails | Leadership changes at Edwards Lifesciences | Drinking habits & heart health
Monday, July 28, 2025
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Today's News and Trends

How to choose between CABG and PCI when treating coronary artery disease

John Puskas, MD, chief of cardiothoracic surgery at Emory University Hospital Midtown, noted that both treatment options have their own benefits. It often depends on the patient's age and comorbidities, though there are other factors to consider as well. 

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John D. Puskas, MD, MSc, PhD., FACS, FACC, professor of surgery, and chief of cardiothoracic surgery at Emory University Hospital Midtown, explains when patients are best served with coronary artery bypass graft (CABG) surgery rather than percutaneous coronary intervention (PCI).
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How to choose between CABG and PCI when treating coronary artery disease

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John D. Puskas, MD, MSc, PhD., FACS, FACC, professor of surgery, and chief of cardiothoracic surgery at Emory University Hospital Midtown, explains when patients are best served with coronary artery bypass graft (CABG) surgery rather than percutaneous coronary intervention (PCI).
John Puskas, MD, chief of cardiothoracic surgery at Emory University Hospital Midtown, noted that both treatment options have their own benefits. It often depends on the patient's age and comorbidities, though there are other factors to consider as well. 
READ MORE >

New drug candidate for AFib fails in first-in-human trial—in fact, it made matters worse

Researchers had thought 2-HOBA might reduce the risk of AFib recurrence after catheter ablation procedures. What they found, however, was that treatment with the compound was actually harmful for patients instead of helpful. 

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pharmaceutical drug approval process
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New drug candidate for AFib fails in first-in-human trial—in fact, it made matters worse

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pharmaceutical drug approval process
Researchers had thought 2-HOBA might reduce the risk of AFib recurrence after catheter ablation procedures. What they found, however, was that treatment with the compound was actually harmful for patients instead of helpful. 
READ MORE >

Edwards Lifesciences loses TAVR leader to robotics firm, announces replacement

The change comes at a momentous time for the company's TAVR portfolio, which made history in May by receiving the very first FDA approval for treating asymptomatic severe AS.

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Larry Wood
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Edwards Lifesciences loses TAVR leader to robotics firm, announces replacement

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Larry Wood
The change comes at a momentous time for the company's TAVR portfolio, which made history in May by receiving the very first FDA approval for treating asymptomatic severe AS.
READ MORE >

How drinking habits influence heart health

Prior studies have already evaluated how individual drinks affect the heart—but what about a person's beverage choices over an extended period of time?

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How drinking habits influence heart health

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Prior studies have already evaluated how individual drinks affect the heart—but what about a person's beverage choices over an extended period of time?
READ MORE >

Featured Articles

Trump administration takes aim at ultra-processed foods, highlighting heart risks

The FDA and other federal agencies believe limiting ultra-processed foods can help "Make America Healthy Again." They highlighted years of research linking these foods to increased risks of cardiovascular disease, type 2 diabetes and other conditions. 

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Trump and Robert F. Kennedy Jr., secretary of health and human services (HHS). White House press photo
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Trump administration takes aim at ultra-processed foods, highlighting heart risks

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Trump and Robert F. Kennedy Jr., secretary of health and human services (HHS). White House press photo
The FDA and other federal agencies believe limiting ultra-processed foods can help "Make America Healthy Again." They highlighted years of research linking these foods to increased risks of cardiovascular disease, type 2 diabetes and other conditions. 
READ MORE >

Interest rising in CKM syndrome as connections become clearer

Cardiovascular-kidney-metabolic (CKM) syndrome is a popular research topic among cardiologists, highlighting just how closely obesity, type 2 diabetes, chronic kidney disease and cardiovascular disease are related to one another. Joshua Joseph, MD, spoke to Cardiovascular Business about this ongoing trend.

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Joshua Joseph, MD, MPH, FAHA an expert in Cardiovascular-Kidney-Metabolic (CKM) syndrome, associate professor of internal medicine, and the Endowed Professor for Research in Internal Medicine in the Division of Endocrinology, Diabetes and Metabolism at The Ohio State University Wexner Medical Center, explains the CKM advisory from the American Heart Association designed to help define and stage the disease. CKM has seen a large amount of growing interest from cardiologists in recent years.
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Interest rising in CKM syndrome as connections become clearer

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Joshua Joseph, MD, MPH, FAHA an expert in Cardiovascular-Kidney-Metabolic (CKM) syndrome, associate professor of internal medicine, and the Endowed Professor for Research in Internal Medicine in the Division of Endocrinology, Diabetes and Metabolism at The Ohio State University Wexner Medical Center, explains the CKM advisory from the American Heart Association designed to help define and stage the disease. CKM has seen a large amount of growing interest from cardiologists in recent years.
Cardiovascular-kidney-metabolic (CKM) syndrome is a popular research topic among cardiologists, highlighting just how closely obesity, type 2 diabetes, chronic kidney disease and cardiovascular disease are related to one another. Joshua Joseph, MD, spoke to Cardiovascular Business about this ongoing trend.
READ MORE >

New gene therapy for rare heart condition gains FDA’s fast track designation

Catecholaminergic polymorphic ventricular tachycardia is a rare, potentially fatal heart rhythm disorder. A new gene therapy candidate from Solid Biosciences is now one step closer to FDA approval. 

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Compensation for U.S. cardiologists is up across the board, according to a recent survey published by MedAxiom, an American College of Cardiology company. The report identified similar trends for cardiovascular surgeons, highlighting the country’s high demand for all heart specialists in 2024 and beyond.
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New gene therapy for rare heart condition gains FDA’s fast track designation

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Compensation for U.S. cardiologists is up across the board, according to a recent survey published by MedAxiom, an American College of Cardiology company. The report identified similar trends for cardiovascular surgeons, highlighting the country’s high demand for all heart specialists in 2024 and beyond.
Catecholaminergic polymorphic ventricular tachycardia is a rare, potentially fatal heart rhythm disorder. A new gene therapy candidate from Solid Biosciences is now one step closer to FDA approval. 
READ MORE >

Complications after intravascular lithotripsy are rare, real-world data confirm

Shockwave Medical, now a part of Johnson & Johnson MedTech, has consistently been found safe for patients. However, many previous clinical trials excluded high-risk patients, making it important to track real-world outcomes as time goes on.

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The use of intravascular lithotripsy (IVL) during percutaneous coronary intervention (PCI) is still safe and effective when patients present with calcified nodules (CNs), according to new long-term data published in EuroIntervention.[1] Researchers compared outcomes from patients with and without CNs, highlighting key similarities in stent expansion and luminal gain.
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Complications after intravascular lithotripsy are rare, real-world data confirm

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The use of intravascular lithotripsy (IVL) during percutaneous coronary intervention (PCI) is still safe and effective when patients present with calcified nodules (CNs), according to new long-term data published in EuroIntervention.[1] Researchers compared outcomes from patients with and without CNs, highlighting key similarities in stent expansion and luminal gain.
Shockwave Medical, now a part of Johnson & Johnson MedTech, has consistently been found safe for patients. However, many previous clinical trials excluded high-risk patients, making it important to track real-world outcomes as time goes on.
READ MORE >

In Case You Missed It

FDA details multiple Class I recalls for Edwards Lifesciences surgical devices

Edwards Lifesciences has recalled more than 61,000 medical devices due to the risk of a small piece of wire becoming exposed. No patient injuries have been reported at this time.

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Product Recall
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FDA details multiple Class I recalls for Edwards Lifesciences surgical devices

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Product Recall
Edwards Lifesciences has recalled more than 61,000 medical devices due to the risk of a small piece of wire becoming exposed. No patient injuries have been reported at this time.
READ MORE >

FDA approves Bayer's finerenone to treat wide range of heart failure patients

Finerenone, sold by Bayer under the brand name Kerendia, is now approved in the United States for the treatment of HFmrEF and HFpEF. The drug has already been used for years to treat patients with chronic kidney disease and type 2 diabetes.

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Bayer finerenone Kerendia heart failure MOONRAKER
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FDA approves Bayer's finerenone to treat wide range of heart failure patients

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Bayer finerenone Kerendia heart failure MOONRAKER
Finerenone, sold by Bayer under the brand name Kerendia, is now approved in the United States for the treatment of HFmrEF and HFpEF. The drug has already been used for years to treat patients with chronic kidney disease and type 2 diabetes.
READ MORE >

CMS proposes Medicare coverage for renal denervation

This proposal, if finalized, would dramatically increase patient access to renal denervation. Both Recor Medical and Medtronic have shared their excitement over the news.

READ MORE >
The Medtronic Symplicity Spyral Renal Denervation system uses a catheter that curls in the renal artery to place radiofrequency electrodes against the vessel wall to ablate the nerves that control vasodilation, so the artery can be propped in the fully open position.
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CMS proposes Medicare coverage for renal denervation

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The Medtronic Symplicity Spyral Renal Denervation system uses a catheter that curls in the renal artery to place radiofrequency electrodes against the vessel wall to ablate the nerves that control vasodilation, so the artery can be propped in the fully open position.
This proposal, if finalized, would dramatically increase patient access to renal denervation. Both Recor Medical and Medtronic have shared their excitement over the news.
READ MORE >

In Other News

Society of Interventional Radiology opposes value-based care proposal

Under the proposal, Medicare would add an interventional radiology payment pathway, creating a new reporting framework for IRs as part of MIPS.

READ MORE >
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Society of Interventional Radiology opposes value-based care proposal

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Under the proposal, Medicare would add an interventional radiology payment pathway, creating a new reporting framework for IRs as part of MIPS.
READ MORE >

VA redirects $800M to upgrade EHR systems, infrastructure

The Department of Veterans Affairs said the new funding was made possible by its cost-saving measures, including a reduction of 30,000 staff and the consolidation of call centers.

READ MORE >
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VA redirects $800M to upgrade EHR systems, infrastructure

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The Department of Veterans Affairs said the new funding was made possible by its cost-saving measures, including a reduction of 30,000 staff and the consolidation of call centers.
READ MORE >

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