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FDA approves oral semaglutide for reducing cardiovascular risks | PET & carotid plaque | AFib after CABG | Nonobstructive HCM

News You Need to Know Today
FDA approves oral semaglutide for reducing cardiovascular risks | PET & carotid plaque | AFib after CABG | Nonobstructive HCM
Monday, October 20, 2025
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Today's News and Trends

FDA approves oral semaglutide for reducing cardiovascular risks in adults with type 2 diabetes

Rybelsus from Novo Nordisk is officially the first oral GLP-1 drug approved for this indication. The FDA's decision was based on the SOUL trial, which included data from more than 9,000 patients with type 2 diabetes.

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FDA approves oral semaglutide for reducing cardiovascular risks in adults with type 2 diabetes

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approval regulations checkmark doctor
Rybelsus from Novo Nordisk is officially the first oral GLP-1 drug approved for this indication. The FDA's decision was based on the SOUL trial, which included data from more than 9,000 patients with type 2 diabetes.
READ MORE >

PET holds promise for carotid plaque assessments

PET has already gained significant momentum in recent years. Now, researchers are pointing to another possible use for the popular imaging modality: assessing carotid artery atherosclerosis.

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Positron emission tomography (PET) nuclear imaging has seen rapid expansion in cardiology and oncology due to its improve accuracy over SPECT and its ability to expand into new areas of cardiovascular imaging. A new review in the American Heart Association journal Stroke outlines another possible use of PET to assess carotid artery atherosclerosis for stroke prevention. Figure courtesy Stroke, https://www.ahajournals.org/doi/10.1161/STROKEAHA.125.050399
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PET holds promise for carotid plaque assessments

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Positron emission tomography (PET) nuclear imaging has seen rapid expansion in cardiology and oncology due to its improve accuracy over SPECT and its ability to expand into new areas of cardiovascular imaging. A new review in the American Heart Association journal Stroke outlines another possible use of PET to assess carotid artery atherosclerosis for stroke prevention. Figure courtesy Stroke, https://www.ahajournals.org/doi/10.1161/STROKEAHA.125.050399
PET has already gained significant momentum in recent years. Now, researchers are pointing to another possible use for the popular imaging modality: assessing carotid artery atherosclerosis.
READ MORE >

New-onset AFib is common after CABG—but typically not persistent or symptomatic

The study's authors questioned if these patients should even be given oral anticoagulation as currently recommended.

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New-onset AFib is common after CABG—but typically not persistent or symptomatic

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heart data research doctor cardiologist AI
The study's authors questioned if these patients should even be given oral anticoagulation as currently recommended.
READ MORE >

Hypertrophic Cardiomyopathy Association supports study of potential treatment for nonbstructive HCM

No medications are currently approved for the treatment of nonobstructive hypertrophic cardiomyopathy. Could a new drug from Imbria Pharmaceuticals be the first?

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Imbria Pharmaceuticals announced a partnership with the Hypertrophic Cardiomyopathy Association (HCMA) to help expedite patient recruitment for its ongoing FORTITUDE-HCM study looking at the first drug to treat symptomatic nonobstructive hypertrophic cardiomyopathy (nHCM). The debilitating disease currently has no approved treatments.
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Hypertrophic Cardiomyopathy Association supports study of potential treatment for nonbstructive HCM

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Imbria Pharmaceuticals announced a partnership with the Hypertrophic Cardiomyopathy Association (HCMA) to help expedite patient recruitment for its ongoing FORTITUDE-HCM study looking at the first drug to treat symptomatic nonobstructive hypertrophic cardiomyopathy (nHCM). The debilitating disease currently has no approved treatments.
No medications are currently approved for the treatment of nonobstructive hypertrophic cardiomyopathy. Could a new drug from Imbria Pharmaceuticals be the first?
READ MORE >

Hospital in Mexico earns first heart failure certification of its kind

A facility outside the United States has received the American Heart Association's Comprehensive Heart Failure Center Certification for the first time.

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Hospital staff walking through a medical facility, intentionally blurred to look artistic
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Hospital in Mexico earns first heart failure certification of its kind

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Hospital staff walking through a medical facility, intentionally blurred to look artistic
A facility outside the United States has received the American Heart Association's Comprehensive Heart Failure Center Certification for the first time.
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Featured Articles

Advances in imaging could help predict, prevent heart attacks

Imagers can now identify vulnerable plaques that were once very challenging to find. The next steps include improving the screening process and determining which lesions need to be treated right away.

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James Muller, MD, explains advances in vulnerable plaque imaging aim to predict and prevent heart attacks.
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Advances in imaging could help predict, prevent heart attacks

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James Muller, MD, explains advances in vulnerable plaque imaging aim to predict and prevent heart attacks.
Imagers can now identify vulnerable plaques that were once very challenging to find. The next steps include improving the screening process and determining which lesions need to be treated right away.
READ MORE >

SGLT2 inhibitors after TAVR may boost survival, limit bioprosthetic valve dysfunction

Prescribing these drugs to TAVR patients could improve certain clinical outcomes, according to a new study of nearly 27,000 adults. 

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SGLT2 inhibitors after TAVR may boost survival, limit bioprosthetic valve dysfunction

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heart drugs with stethoscope
Prescribing these drugs to TAVR patients could improve certain clinical outcomes, according to a new study of nearly 27,000 adults. 
READ MORE >

Field Medical’s PFA system for ventricular tachycardia shows early potential

More research is still required, but Field Medical's FieldForce Ablation System may represent a significant step forward in the treatment of scar-related ventricular tachycardia.

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Field Medical's FieldForce pulsed field ablation system. Image courtesy of Field Medical.
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Field Medical’s PFA system for ventricular tachycardia shows early potential

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Field Medical's FieldForce pulsed field ablation system. Image courtesy of Field Medical.
More research is still required, but Field Medical's FieldForce Ablation System may represent a significant step forward in the treatment of scar-related ventricular tachycardia.
READ MORE >

FDA clears AI-powered vascular imaging software

The new software provides automated measurements that save time and improve the care of aortic aneurysm patients. 

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Nurea PRAEVAorta 2
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FDA clears AI-powered vascular imaging software

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Nurea PRAEVAorta 2
The new software provides automated measurements that save time and improve the care of aortic aneurysm patients. 
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In Case You Missed It

Obesity drugs under review: Semaglutide, tirzepatide, naltrexone/bupropion all boost heart health

The popularity of various obesity management medications has increased significantly in recent years. According to a new analysis of more than 60,000 patients, some of these drugs are associated with more cardiovascular benefits than others.

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obesity semaglutide tirzepatide GLP-1 drugs weight loss
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Obesity drugs under review: Semaglutide, tirzepatide, naltrexone/bupropion all boost heart health

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obesity semaglutide tirzepatide GLP-1 drugs weight loss
The popularity of various obesity management medications has increased significantly in recent years. According to a new analysis of more than 60,000 patients, some of these drugs are associated with more cardiovascular benefits than others.
READ MORE >

SCAI highlights the benefits of ICE-guided structural heart interventions

ICE is gaining momentum as a helpful imaging option during structural heart interventions, according to a new SCAI position statement. TEE and TTE remain incredibly important, but there are times when ICE can provide the guidance necessary.

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SCAI ICE position statement
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SCAI highlights the benefits of ICE-guided structural heart interventions

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SCAI ICE position statement
ICE is gaining momentum as a helpful imaging option during structural heart interventions, according to a new SCAI position statement. TEE and TTE remain incredibly important, but there are times when ICE can provide the guidance necessary.
READ MORE >

AI-powered cardiac mapping system gains an important approval

The vMap System from San Diego-based Vektor Medical turns 12-lead ECGs into 3D maps of the heart. It has already been cleared by the FDA.

READ MORE >
The Vektor Medical vMap system takes standard 12-lead ECGs and converts them into detailed electro anatomical maps for us in catheter ablation procedures.
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AI-powered cardiac mapping system gains an important approval

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The Vektor Medical vMap system takes standard 12-lead ECGs and converts them into detailed electro anatomical maps for us in catheter ablation procedures.
The vMap System from San Diego-based Vektor Medical turns 12-lead ECGs into 3D maps of the heart. It has already been cleared by the FDA.
READ MORE >

In Other News

How one hospital more than doubled its lung cancer screening rate

It is estimated that less than 20% of eligible patients in the U.S. adhere to LCS recommendations, despite numerous studies highlighting the exam’s effectiveness. 

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lung cancer screening
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How one hospital more than doubled its lung cancer screening rate

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lung cancer screening
It is estimated that less than 20% of eligible patients in the U.S. adhere to LCS recommendations, despite numerous studies highlighting the exam’s effectiveness. 
READ MORE >

Hemp and other plant-based compounds could be future of contrast-enhanced imaging

Experts are working to develop agents they say can enhance imaging studies without the risks associated with traditional contrast media. 

READ MORE >
hemp-leaf-3661209_960_720.jpg
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Hemp and other plant-based compounds could be future of contrast-enhanced imaging

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hemp-leaf-3661209_960_720.jpg
Experts are working to develop agents they say can enhance imaging studies without the risks associated with traditional contrast media. 
READ MORE >

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