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New gene therapy targets a challenging condition | Big news out of Mount Sinai | First patients treated in PFA trial

News You Need to Know Today
New gene therapy targets a challenging condition | Big news out of Mount Sinai | First patients treated in PFA trial
Thursday, April 9, 2026
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Today's News and Trends

New gene therapy may help protect the hearts of patients with Friedreich's ataxia

A majority of deaths from Friedreich's ataxia are associated with heart complications. A new treatment years in the making could provide some much-needed relief.

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Video interview with Ronald Crystal, MD, chair, Department of Genetic Medicine at Weill Cornell Medicine, presented late-breaking findings on a first in-human, virus-delivered gene therapy trial to stop cardiomyopathy death in patients with Friedreich Ataxia (FA). #ACC #ACC26
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New gene therapy may help protect the hearts of patients with Friedreich's ataxia

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Video interview with Ronald Crystal, MD, chair, Department of Genetic Medicine at Weill Cornell Medicine, presented late-breaking findings on a first in-human, virus-delivered gene therapy trial to stop cardiomyopathy death in patients with Friedreich Ataxia (FA). #ACC #ACC26
A majority of deaths from Friedreich's ataxia are associated with heart complications. A new treatment years in the making could provide some much-needed relief.
READ MORE >

Mount Sinai announces new global center focused on heart valve disease

The Adams Valve Institute—named after David H. Adams, MD—plans on uniting specialists to provide high-quality care, promote innovation and advocate for policy reform.

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The leaders of the new Adams Valve Institute at Mount Sinai are Ismail El-Hamamsy, MD, PhD, director of aortic surgery and director of the Adams Valve Institute (left), and David H. Adams, MD, the Marie-Josée and Henry R. Kravis Professor and chair of the Department of Cardiovascular Surgery at the Icahn School of Medicine, and cardiac surgeon-in-chief of the Mount Sinai Health System.
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Mount Sinai announces new global center focused on heart valve disease

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The leaders of the new Adams Valve Institute at Mount Sinai are Ismail El-Hamamsy, MD, PhD, director of aortic surgery and director of the Adams Valve Institute (left), and David H. Adams, MD, the Marie-Josée and Henry R. Kravis Professor and chair of the Department of Cardiovascular Surgery at the Icahn School of Medicine, and cardiac surgeon-in-chief of the Mount Sinai Health System.
The Adams Valve Institute—named after David H. Adams, MD—plans on uniting specialists to provide high-quality care, promote innovation and advocate for policy reform.
READ MORE >

First patients treated in new PFA trial

The new nPulse nanosecond pulsed field ablation system uses five‑second applications to create lesions. It does not require catheter repositioning.

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Pulse Biosciences nPulse nanosecond pulsed field ablation (nsPFA) system uses 5‑second applications to create lesions and does not require catheter repositioning.
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First patients treated in new PFA trial

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Pulse Biosciences nPulse nanosecond pulsed field ablation (nsPFA) system uses 5‑second applications to create lesions and does not require catheter repositioning.
The new nPulse nanosecond pulsed field ablation system uses five‑second applications to create lesions. It does not require catheter repositioning.
READ MORE >

Featured Articles

Johnson & Johnson launches faster PFA system in Europe

The new version of the PFA system is five times faster than the current catheter to improve workflow.

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Johnson & Johnson announced the launch of its new Varipulse Pro pulsed field ablation (PFA) system in Europe following CE mark approval. It is five times faster at ablation delivery at a cooler temperature than the previous version.
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Johnson & Johnson launches faster PFA system in Europe

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Johnson & Johnson announced the launch of its new Varipulse Pro pulsed field ablation (PFA) system in Europe following CE mark approval. It is five times faster at ablation delivery at a cooler temperature than the previous version.
The new version of the PFA system is five times faster than the current catheter to improve workflow.
READ MORE >

Long-term cardiac amyloidosis survival benefits seen in extension acoramidis trial

Patient outcomes clearly show acoramidis reduces both all-cause mortality and cardiovascular hospitalizations, but the study also reinforced the importance of early diagnosis and prompt medical therapy. 
 

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Prem Soman, MD, director of the Cardiac Amyloidosis Center and nuclear cardiology, and associate chief of cardiology at the University of Pittsburgh Medical Center Heart and Vascular Institute presented the late-breaking results from the long-term survival benefits and disease stabilization with the drug acoramidis in patients with transthyretin amyloid cardiomyopathy at ACC 2026.
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Long-term cardiac amyloidosis survival benefits seen in extension acoramidis trial

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Prem Soman, MD, director of the Cardiac Amyloidosis Center and nuclear cardiology, and associate chief of cardiology at the University of Pittsburgh Medical Center Heart and Vascular Institute presented the late-breaking results from the long-term survival benefits and disease stabilization with the drug acoramidis in patients with transthyretin amyloid cardiomyopathy at ACC 2026.
Patient outcomes clearly show acoramidis reduces both all-cause mortality and cardiovascular hospitalizations, but the study also reinforced the importance of early diagnosis and prompt medical therapy.  
READ MORE >

FDA clears way for IDE pivotal trial of the Topaz tricuspid valve replacement system

The TRiCares Topaz uses a unique two-stent frame valve prosthesis for better sealing and flexibility.

READ MORE >
The U.S. Food and Drug Administration (FDA) has approved an investigational device exemption (IDE) to conduct a pivotal clinical trial for TRiCares Topaz transcatheter tricuspid valve replacement (TTVR) system in the U.S. The TTVR system uses two stent frames, one for the valve and one to engage the annulus with a membrane shirt between them to enable flexing of the outer ring to better seal against regurgitation.expansing stents
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FDA clears way for IDE pivotal trial of the Topaz tricuspid valve replacement system

Share on Twitter Share on Facebook Share on Linkedin
The U.S. Food and Drug Administration (FDA) has approved an investigational device exemption (IDE) to conduct a pivotal clinical trial for TRiCares Topaz transcatheter tricuspid valve replacement (TTVR) system in the U.S. The TTVR system uses two stent frames, one for the valve and one to engage the annulus with a membrane shirt between them to enable flexing of the outer ring to better seal against regurgitation.expansing stents
The TRiCares Topaz uses a unique two-stent frame valve prosthesis for better sealing and flexibility.
READ MORE >

In Case You Missed It

Court affirms death sentence for Texas nurse who intentionally killed patients

A jury sentenced the former cardiovascular ICU nurse to death for intentionally murdering multiple heart patients. In one TV interview, he said the power associated with the murders became "an addiction" over time. 

READ MORE >
judge court gavel justice system legal
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Court affirms death sentence for Texas nurse who intentionally killed patients

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judge court gavel justice system legal
A jury sentenced the former cardiovascular ICU nurse to death for intentionally murdering multiple heart patients. In one TV interview, he said the power associated with the murders became "an addiction" over time. 
READ MORE >

New obesity statistics highlight importance of preventive cardiology

Cardiovascular health is much worse in some parts of the United States than others. Cardiologists in those high-risk areas can make a world of difference by embracing preventive cardiology and working to treat patients before it is too late.

READ MORE >
doctor with overweight patient who may be treated with TAVR or surgery
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New obesity statistics highlight importance of preventive cardiology

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doctor with overweight patient who may be treated with TAVR or surgery
Cardiovascular health is much worse in some parts of the United States than others. Cardiologists in those high-risk areas can make a world of difference by embracing preventive cardiology and working to treat patients before it is too late.
READ MORE >

Trump’s EPA wants to roll back Biden-era pollution limits for medical device sterilization

Ethylene oxide is an odorless gas used to sterilize pacemakers, leads, stents and many other medical devices. Long-term exposure, however, can cause cancer. The Biden administration made it a priority to reduce ethylene oxide emissions, but many critics thought those cuts were too extreme.  

READ MORE >
President Donald Trump, White House press photo.
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Trump’s EPA wants to roll back Biden-era pollution limits for medical device sterilization

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President Donald Trump, White House press photo.
Ethylene oxide is an odorless gas used to sterilize pacemakers, leads, stents and many other medical devices. Long-term exposure, however, can cause cancer. The Biden administration made it a priority to reduce ethylene oxide emissions, but many critics thought those cuts were too extreme.  
READ MORE >

In Other News

With pro bono legal help, hospital workers ‘send union bosses packing’

Employees at a 130-bed hospital whose home state lacks right-to-work protections are now free to work without having to join a powerful union that had sought to represent them. 

READ MORE >
Thumbs Down
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With pro bono legal help, hospital workers ‘send union bosses packing’

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Thumbs Down
Employees at a 130-bed hospital whose home state lacks right-to-work protections are now free to work without having to join a powerful union that had sought to represent them. 
READ MORE >

AI is everywhere ... except in radiology job postings, new data reveal

Talk of artificial intelligence in radiology is commonplace these days, but a new report suggests that employers are remaining mum on the topic when it comes to job descriptions.

READ MORE >
AI artificial intelligence stethoscope doctor
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AI is everywhere ... except in radiology job postings, new data reveal

Share on Twitter Share on Facebook Share on Linkedin
AI artificial intelligence stethoscope doctor
Talk of artificial intelligence in radiology is commonplace these days, but a new report suggests that employers are remaining mum on the topic when it comes to job descriptions.
READ MORE >

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