Links to all the late-breaking trials for Heart Rhythm 2023

The Heart Rhythm Society (HRS) has released the full list of late-breaking electrophysiology (EP) studies planned for its Heart Rhythm 2023 annual meeting in New Orleans. The meeting is scheduled to take place from Friday, May 19 through Sunday, May 21.

The meeting includes more than 7,700 attendees in the field of cardiac pacing and EP. More than 700 international experts in the field serve as faculty for more than 200 educational sessions. About 120 exhibitors exhibit on the expo floor. 

Late Breaking Clinical Trials and Science - Ablation
Friday, May 19, 11 a.m. - noon, Great Hall A

   • Pre-ablation Weight Loss as a Predictor of Atrial Fibrillation Ablation Outcome in the Liraglutide Effect on Atrial Fibrillation (LEAF) Study. Presented by Jeffrey Goldberger, MD, University of Miami.

   • Long-term Clinical Outcomes of Pulsed Field Ablation to Treat Patients with Paroxysmal Atrial Fibrillation. Presented by Daniel Musikantow, MD, Mount Sinai Hospital.

   • World-wide Experience With an End-Hole Irrigated Needle Catheter for Ablation of Refractory Ventricular Arrhythmias: Final Report. Presented by Usha Tedrow, MD, Brigham and Women`s Hospital.

   • Influence of Atrial Arrhythmia Burden on Quality of Life in Patients Undergoing Pulsed Field Ablation: A sub-study of the PULSED AF trial. Presented by Atul Verma, MD, McGill University Health Centre.

Late Breaking Clinical Trials and Science - Ventricular Arrhythmias
Friday, May 19, 3:30 - 4:30 p.m., Great Hall A

   • Contemporary Outcomes of Non-ischemic Cardiomyopathy Patients With an Implanted Defibrillator or Cardiac Resynchronization Therapy (BIO-LIBRA). Presented. By Valentina Kutyifa, MD, University of Rochester Medical Center.

   • Effects of Implantable Cardioverter-defibrillator Leads on the Tricuspid Valve and Right Ventricle: A Randomized Comparison of Transvenous Versus Subcutaneous Leads. Presented by Darryl Leong, PhD, McMaster University.

   • Long-Term Results from a Prospective Phase 1/2 Trial of Electrophysiology Guided Noninvasive Cardiac Radio-ablation for Ventricular Tachycardia. Presented by Phillip Cuculich, MD, Washington University in St. Louis. 

   • Near-Term Prediction of Life-Threatening Ventricular Arrhythmias Using Artificial Intelligence-enabled Single Lead Ambulatory ECG. Presented by Eloi Marijon, MD, Hôpital Européen Georges-Pompidou.

Late Breaking Clinical Trials and Science - AF
Saturday, May 20, 9:30 - 10:30 a.m., Great Hall A

   • Unexpected Increase in Postoperative Atrial Fibrillation by Calcium-mediated Autonomic Denervation: The CAP-AF2 Randomized Clinical Trial. Presented by Sunny Po, MD, University of Oklahoma Heart Rhythm Institute.

   • Dynamic Data Driven Management of Atrial Fibrillation Using Implantable Cardiac Monitors – The MONITOR AF Study. Presented by Dhanunjaya Lakkireddy, MD, The Kansas City Heart Rhythm Institute at HCA Midwest Health.

   •  EUropean Real World Outcomes With Pulsed Field AblatiOn in Patients with Symptomatic AtRIAl Fibrillation - Lessons from the multicenter EU-PORIA Registry. Presented by Boris Schmidt, MD, Cardioangiologisches Centrum Bethanien, Frankfurt, Germany.

   • Low Energy Multi-Pulse Therapy for Cardioversion of AF in Humans. Presented by Prashanthan Sanders, MBBS, University of Adelaide.

Late Breaking Clinical Trials and Science - Innovations
Saturday, May 20, 2 - 3 p.m., Great Hall A

   • Percutaneous implantation of a dual chamber leadless cardiac pacemaker system with bidirectional communication for atrioventricular synchrony (Aveir dual-chamber i2i). Presented by Daniel Cantillon, MD, Cleveland Clinic.
 
  • Multicenter First in Human Clinical Feasibility Study to Evaluate Safety and Efficacy of Low Energy Multi-pulse Therapy for Ventricular Tachycardia. Presented by Venkatakrishna Tholakanahalli, MD, Minneapolis VA Health Care System. 

   • First-in-man Experience With the Impella 5.0/5.5 Hemodynamic Support Device for High-Risk Patients with Advanced Heart Failure Undergoing VT Ablation. Presented by Jakub Sroubek, MD, Cleveland Clinic.

   • Noninvasive Ear Clip for Vagus Nerve Stimulation in Postural Tachycardia Syndrome (POTS): A Randomized Clinical Trial. Presented by Stavros Stavrakis, MD, University of Oklahoma.

Late Breaking Clinical Trials and Science - Cardiovascular Implantable Electronic Device (CIED)
Saturday, May 20, 3:30 - 4:30 p.m., Great Hall A

   • First results of the randomized PRAETORIAN-DFT trial: Prospective validation of the PRAETORIAN score for prediction of defibrillation test success after subcutaneous ICD implant. Presented by Reinoud Knops, MD, Academic Medical Center, Amsterdam.

   • Chronic Safety and Performance of the Extravascular ICD: Results From the Global EV ICD Pivotal Study. Presented by Paul Friedman, MD, Mayo Clinic.

   • His-purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy Versus Biventricular Pacing: A randomized controlled clinical trial (HOT-CRT). Presented by Pugazhendhi Vijayaraman, MD, Geisinger Heart Institute.

   • MAgnetic resonance imaging based DUal lead cardiac Resynchronization therapy: A prospectIve Left Bundle Branch Pacing Study (MADURAI LBBP study). Presented by Shunmuga Sundaram Ponnusamy, MBBS, MD, Velammal Medical College Hospital and Research Institute.