CRF announces late-breaking clinical trials for TCT 2024
The Cardiovascular Research Foundation (CRF) has announced the full lineup of late-breaking clinical trials and late-breaking clinical science scheduled for TCT 2024 in Washington, DC.
TCT 2024 takes place Oct. 27-30 at the Walter E. Washington Convention Center. This is the 36th annual Transcatheter Cardiovascular Therapeutics Conference. What started in 1988 as a gathering of 150 heart specialists is now widely regarded as one of interventional cardiology’s most important, influential conferences.
Topics to be discussed during the four-day event include transcatheter aortic valve replacement (TAVR) and other structural heart procedures, cerebral protection devices, pharmaceutical treatments and much more.
Late-breaking clinical trials at TCT 2024
Monday, October 28
Early TAVR
Transcatheter Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis: Results of the EARLY TAVR Trial.
This session will be presented by Philippe Genereux.
TAVR UNLOAD
Transcatheter Aortic Valve Replacement in Patients With Systolic Heart Failure and Moderate Aortic Stenosis.
This session will be presented by Nicholas M. Van Mieghem.
EVOLVED
Early Intervention in Patients With Asymptomatic Severe Aortic Stenosis and Left Ventricular Myocardial Fibrosis.
This session will be presented by Marc Dweck.
Tuesday, October 29
ECLIPSE
A Large-Scale, Randomized Trial of Orbital Atherectomy vs. Conventional Balloon Angioplasty in Severely Calcified Coronary Arteries Prior to DES Implantation.
This session will be presented by Ajay J. Kirtane.
CLEAR SYNERGY (OASIS 9)
A 2x2 Factorial Randomized Controlled Trial of Colchicine vs. Placebo, and Spironolactone vs. Placebo in Patients With Myocardial Infarction: Results of the Colchicine Factorial.
This session will be presented by Sanjit S. Jolly.
PEERLESS
Large-Bore Mechanical Thrombectomy vs. Catheter-Directed Thrombolysis for Treatment of Intermediate-Risk Pulmonary Embolism.
This session will be presented by Wissam A. Jaber.
SIRONA
Head-to-Head Comparison of Sirolimus- vs. Paclitaxel-Coated Balloon Angioplasty in the Femoropopliteal Artery.
This session will be presented by Ulf Teichgraeber.
Wednesday, October 30
TRISCEND II
Randomized Comparison of Transcatheter Valve Replacement vs. Optimal Medical Therapy for Severe Tricuspid Regurgitation
This session will be presented by Susheel K. Kodali and Suzanne V. Arnold.
ACURATE IDE
One-year Outcomes of Acurate neo2 vs. Approved TAVR Devices in All-risk patients with Severe AS.
This session will be presented by Michael J. Reardon.
FAVOR III Europe
Quantitative Flow Ratio or Fractional Flow Reserve for Guiding Coronary Revascularization
This session will be presented by Birgitte Krogsgaard Andersen.
FLASH
Artificial Intelligence-Based Fully Automated Quantitative Coronary Angiography vs. Optical Coherence Tomography Guidance for Coronary Stent Implantation: A Multicenter, Randomized Controlled Non-Inferiority Trial
This session will be presented by Jung-Min Ahn.
Late-breaking clinical science at TCT 2024
Monday, October 28
DCB-BIF
Comparison of Noncompliant Balloon With Drug-Coated Balloon Angioplasty for Side Branch Stenosis After Provisional Stenting for Patients With True Coronary Bifurcation Lesions
This session will be presented by ShaoLiang Chen.
HELP PCI
Early Administration of Heparin at First Medical Contact vs. in the Cath Lab for STEMI Patients Undergoing Primary Percutaneous Coronary Intervention: A Multicenter, Randomized Trial.
This session will be presented by Jing Chen.
DRAMI
Randomized Comparison of Puncture Success Rate Between Distal Radial Access and Transradial Access in Patients With ST-Elevation Myocardial Infarction
This session will be presented by Jun-Won Lee.
INFINITY-SWEDEHEART Complex PCI
1-Year and Landmark 6–12 Month Clinical Outcomes Among Patients With Complex Lesion Subsets Treated With DynamX Bioadaptor Compared to a Contemporary Drug Eluting Stent
This session will be presented by David Erlinge.
CONFIRM-2
Artificial Intelligence Enabled Quantitative CT Assessment of Atherosclerosis and Major Adverse Events: A Multi-Center International Registry
This session will be presented by Alexander Van Rosendael.
Tuesday, October 29
Co-STAR
Colchicine in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Double-Blind Randomized Controlled Trial
This session will be presented by Thomas Pilgrim.
ACCESS TAVI
Randomized Comparison of Strategies for Vascular Access Closure After Transcatheter Aortic Valve Implantation
This session will be presented by Tobias Rheude.
PROTECTED TAVR: US Subgroup
Cerebral Embolic Protection in the U.S. Cohort of the PROTECTED TAVR Randomized Trial
This session will be presented by Raj Makkar.
RHEIA/PARTNER Pooled Analysis in Women
Transcatheter vs. Surgical Aortic Valve Replacement in Women: A Pooled Analysis of the RHEIA and PARTNER 3 Trials
This session will be presented by Didier Tchetche.
ALIGN-AR 2-Year
Two-Year Outcomes of Transcatheter Aortic Valve Replacement With JenaValve Trilogy in High Surgical Risk Patients With Moderate-to-Severe or Severe Native Aortic Regurgitation.
This session will be presented by Torsten P. Vahl.
Wednesday, October 30
TARGET IV
International Multicenter Randomized Assessment of the Firehawk Rapamycin-eluting Coronary Stent System
This session will be presented by Olivier F. Bertrand.
TARGET DAPT
Prospective, Multicenter, Open-Label, Randomized Controlled Trial of 3-Month vs. 12-Month Dual Antiplatelet Therapy After Implantation of the Biodegradable Polymer Firehawk Sirolimus-eluting Coronary Stent
This session will be presented by Junbo Ge.
CLEAR-IE
Outcomes of Percutaneous Mechanical Aspiration in Right-Sided Infective Endocarditis: A Multicenter Registry
This session will be presented by Abdallah El Sabbagh.
CLASP IID 2 Year
RCT and Registry: Two-Year Outcomes of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation
This session will be presented by Raj Makkar.
MATTERHORN: Atrial MR Subgroup
Transcatheter Repair Versus Surgery in Atrial Mitral Regurgitation: Results From the MATTERHORN Trial. This session will be presented by Stephan Baldus.
More information on TCT 2024
Additional details about these late-breaking sessions are available here.
Click here to read through Cardiovascular Business coverage of TCT 2023 in San Francisco, which included live session coverage as well as a series of exclusive video interviews.
Michael has more than 18 years of experience as a professional writer and editor. He has written at length about cardiology, radiology, artificial intelligence and other key healthcare topics.