THT 2025: Late-breaking clinical trials announced for CRF’s heart failure conference

The Cardiovascular Research Foundation (CRF) has announced the full lineup of late-breaking clinical trials for THT 2025, its annual Technology and Heart Failure Therapeutics (THT) conference. THT 2025 will be held Feb. 11-13 at the Omni Boston Hotel at the Seaport in Boston.

CRF is the organization behind TCT, New York Valves and other educational conferences focused on the diagnosis, treatment and long-term management of cardiovascular disease. THT, now in its fourth year, was developed specifically to help care teams take on the rising rates of heart failure in the United States and beyond. 

Attendees are encouraged to leave their ties, jackets and skirts at home and instead embrace more a casual approach, including jeans and sneakers. 

Read below for the full schedule of late-breaking clinical trials:

Late-Breaking Clinical Science I

Tuesday, Feb. 11, 2025 | 9:30-10:45 a.m. ET | Ensemble A-B | Level 2

  • Robotic Surgical Technique for Performing Heart Transplant: Feras Khaliel
  • Left Atrial to Coronary Sinus Shunting In Heart Failure With Mildly Reduced Or Preserved Ejection Fraction: The ALT FLOW Trial (Early Feasibility Study) 2-Year Results: Javed Butler
  • Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS) – The FASTR Trial: James E. Udelson
  • Incidence and Outcome of Early and Late Right Ventricular Failure in Patients with the HeartMate 3 LVAD: A MOMENTUM 3 Analysis: Gabriel Sayer
  • Changes in Seated Pulmonary Artery Pressure in Response To Titration Of Heart Failure Medications During Ambulatory Monitoring: Sandip K. Zalawadiya
  • Impact of Obesity Severity on the Effects of Tirzepatide in HFpEF: The SUMMIT Trial: Barry Borlaug

Late-Breaking Clinical Science II

Tuesday, Feb. 11, 2025 | 5:45-6:45 p.m. ET | Ensemble A-B | Level 2

  • Predictors of Improved vs. Worsened Outcomes After Inter-atrial Shunt Treatment in HFrEF and HFpEF: The RELIEVE-HF Trial: Gregg W. Stone
  • Right Ventricular to Pulmonary Artery Coupling and Clinical Outcomes after Interatrial Shunting in Heart Failure: Stefan Anker
  • Atrial Shunt for Heart Failure with Preserved and Mildly Reduced Ejection Fraction: Five-Year Outcomes in the REDUCE LAP-HF II Trial: Sanjiv J. Shah
  • Duration of Heart Failure, Cardiac Dysfunction and Remodeling, and Response to Atrial Shunt Treatment in HFpEF and HFmrE: Barry Borlaug
  • Cardiac Microcurrent Application for the Reversal of Heart Failure: Eduardo Rame

Late-Breaking Clinical Science III

Wednesday, Feb. 12, 2025 | 8-9:12 a.m. ET | Ensemble A-B | Level 2

  • Safety and Efficacy of the preCARDIA System to Mechanically Reduce Cardiac Preload for Acutely Decompensated Heart Failure: The Expanded VENoUS Heart Failure (VENUS-HF) Early Feasibility Study: Navin K. Kapur
  • Limited Myocardial Necrosis with Intracoronary Supersaturated Oxygen Therapy In Acute Anterior Myocardial Infarction: Initial Experience In Routine Practice: Andreas Schafer
  • Lower Extremity Lymphatic Flow Is Associated With Diuretic Response And Weight Change (Decongestion) In Acute Heart Failure: Jan Biegus
  • Transcatheter Pulmonary Artery Banding [PAB] For HFrEF: Two Year Follow Up And Invasive Exercise Hemodynamics From The Ongoing First-In-Human Trial: Sean P. Pinney
  • A Digital Platform to Optimize Guideline Directed Heart Failure Therapy: Primary Results of the AIM-POWER Randomized Controlled Trial: Akshay Desai
  • Burst Steroid Therapy and Quality of Life in Patients with Acute Heart Failure: Insights From the CORTAHF Trial: Matteo Pagnesi

Late Breaking Clinical Science IV

Thursday, Feb. 13, 2025 | 7-8 a.m. ET | Ensemble E-F | Level 2

  • GSN Ablation Reduces Estimated Stressed Blood Volume in HFpEF: Supports REBALANCE-HF Mechanism of Action: Marat Fudim
  • Real-World Survival Comparison of Symptomatic Patients with Heart Failure Treated with Cardiac Contractility Modulation (CCM) vs. Cardiac Resynchronization Therapy (CRT): Andrew Sauer
  • Impact Of Preoperative Temporary Mechanical Circulatory Support On Durable LVAD Outcomes: An Analysis of the Society Of Thoracic Surgeons National Intermacs Database: Manreet Kanwar
  • Mitigating Post-Operative Right Ventricular Dysfunction After Left Ventricular Assist Device: The RV Protection Study: Anthony Kanelidis
  • PICS: A Novel Temporary CV Support Device Augmenting BP and Flow: Alex M. K. Rothman
Michael Walter
Michael Walter, Managing Editor

Michael has more than 18 years of experience as a professional writer and editor. He has written at length about cardiology, radiology, artificial intelligence and other key healthcare topics.

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