Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Minneapolis Heart Institute Foundation announces its first implant of world's smallest cardiac pacemaker

The Minneapolis Heart Institute Foundation (MHIF) announced today the first implant of the world's smallest pacemaker at the Minneapolis Heart Institute. The device was implanted as part of a global clinical trial and the procedure was the first of its kind in the Midwest.

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HeartWare: Monitor VAD batteries

Heartware International has issued back-to-back warnings about its ventricular assist device (VAD), with the most recent notice involving batteries in the HeartWare Ventricular Assist System.

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Waiting, but not idle

A patient who is on a heart transplant waiting list became the first participant with a total artificial heart to complete the 4.2-mile course at the annual Pat’s Run event in Tucson, Ariz. AZ Central Channel i2 News reported on the accomplishment.

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FDA puts Class I recall on HeartWare device

The FDA issued a Class I recall for the HeartWare Ventricular Assist Device due to a manufacturing flaw.

Heart failure stands out for costly readmissions

Congestive heart failure topped the list for 30-day readmissions of Medicare beneficiaries in 2011 and ranked among the top 10 high-volume conditions for two other payer categories in an analysis released in April.

FDA gives thumbs up to mini ICDs

The FDA approved the latest generation of Boston Scientific’s implantable cardiac devices.

Celladon receives breakthrough therapy designation from FDA for MYDICAR(R), novel, first-in-class therapy in development to treat heart failure

Celladon Corporation, a clinical-stage biotechnology company developing novel therapies for patients with heart failure and other diseases characterized by SERCA enzyme deficiencies, today announced that its lead product candidate, MYDICAR, has been granted breakthrough therapy designation by the U.S. Food and Drug Administration (FDA) for reducing hospitalizations for heart failure in NYHA class III or IV chronic heart failure patients who are NAb negative.

FDA OKs use of biventricular pacing for less severe HF

The FDA expanded the indication for biventricular pacing using two types of cardiac resynchronization therapy devices to treat patients with atrioventricular block and mild to moderate heart failure (HF).

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.