Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Heart failure, heart attack among most common reasons for hospitalization in US

The analysis, published in European Heart Journal Open, also included a look at how COVID-19 may affect these numbers going forward. 

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Statin therapy helps heart failure patients reduce their risk of cancer

The study's authors called for additional research in this area, noting that it may be beneficial to screen all heart failure patients for cancer. 

FDA announces a new myocarditis warning for COVID-19 vaccines as specialists urge Americans to get vaccinated

In a new statement, the CDC, American Heart Association and several other healthcare organizations highlighted the continued importance of vaccination. 

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New metric identifies heart failure patients facing a higher risk of hospitalization or death

This new measurement, researchers explained, can help clinicians target high-risk patients with more aggressive treatments. 

Empagliflozin approved in Europe for treatment of HFrEF

The SGLT2 inhibitor was approved for this new indication based on results from the EMPEROR-Reduced trial.

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Disease progression seen in 18% of asymptomatic heart failure patients within 1 year

Hospitalizations and death are more common among these patients than clinicians might think. 

An encouraging update: Young adults with vaccine-related heart damage see all symptoms resolve

“Given the potential morbidity of COVID-19 infection even in younger adults, the risk-benefit decision for vaccination remains highly favorable," researchers wrote.

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Heart failure patients see long-term benefits after cell therapy

"This is a very important advance in the field of cell therapy and in the management of heart failure," one specialist said. 

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