Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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TAVR valves drive sales growth for Edwards Lifesciences

Edwards Lifesciences reported on Feb. 1 fourth-quarter 2017 sales of $888.5 million, a 16 percent growth year over year. The increase was largely driven by the success of the Transcatheter Heart Valve Therapy division, which brought in $519.3 million in revenue for the quarter

Man discovers rare congenital heart defect at age 40

Enknvally Jayasimha lived for four decades before discovering he had a rare congenital heart defect that kills nearly all babies who don’t have corrective surgery.

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Baseline depression linked to poorer outcomes in TAVR, SAVR

Symptoms of depression are widespread among elderly patients undergoing aortic valve replacement (AVR) surgery, and the condition is associated with as much as a threefold increase in mortality risk a year after the procedure, researchers reported in JAMA Cardiology this week.

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Researchers ID predictors of next-day discharge after ‘minimalist’ TAVR

Next-day discharge after minimalist transcatheter aortic valve replacement (TAVR) was safe for patients who didn’t experience perioperative complications and was linked to better one-year outcomes versus patients discharged later, according to a single-center study published in JACC: Cardiovascular Interventions.

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AHA's 2017 overhaul of valvular heart disease guidelines, broken down

The American Heart Association (AHA) and American College of Cardiology (ACC) rolled out new guidelines for managing valvular heart disease (VHD) in 2017, marking the second overhaul of VHD recommendations in three years—a move attributable to “extensive new data” that have shaped the way clinicians treat valve disease.

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New-generation device, better sizing eliminates TAVR survival disparity between sexes

A larger valve option and more appropriate valve sizing using preprocedural imaging may eliminate the previously reported survival disparity between men and women undergoing transcatheter aortic valve replacement (TAVR), a new study in JACC: Cardiovascular Interventions suggests.

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Tricuspid valve interventions increasing—but mortality rate remains high

Procedures to replace or repair patients’ tricuspid valves (TVs) remain rare but have increased in recent years, according to a study in the Journal of the American College of Cardiology. But despite this increased volume, in-hospital mortality has remained steady at 8.8 percent.

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New TAVR valve achieves lowest rates of paravalvular leak, pacemaker implantation

The Centera transcatheter heart valve (THV) shows promise in addressing the “Achilles’ heel” of transcatheter aortic valve replacement (TAVR), according to Luis Nombela-Franco, MD, PhD, who wrote an editorial about the device’s pivotal study published in the Journal of the American College of Cardiology.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.