Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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MHIF Enrolls the First-in-the-World Patient in Clinical Trial of Minimally Invasive Clip-Based Repair System for Leaky Tricuspid Heart Valves

Minneapolis Heart Institute Foundation® announced it has enrolled the first-in-the-world patient in a clinical study to evaluate a minimally invasive clip-based repair system made by Abbott (a company based near Chicago), for treating people with moderate or severe tricuspid regurgitation (TR), a common condition affecting the right side of the heart.

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Study: All Portico heart valve sizes demonstrate effective short-term performance

All sizes of the Portico TAVR system resulted in effective and safe short-term treatment of high-risk patients, according to a new study.

Risk of stroke in AFib patients associated with aortic curvature

Atrial fibrillation (AFib) heightens stroke risk—but new research shows that this is true only in people with certain aortic shapes. Those with aortic arches that are less curved are more prone to stroke, according to a study published online Aug. 1 in Nature.

3D ultrasound links heart defects, brain development

European researchers have used 3D ultrasound to measure cortical folding, which increases the surface area of the brain and its processing power, in fetuses with congenital heart defects.

Scientists use CRISPR to erase cardiomyopathy mutation in human embryos

CRISPR is capable of targeting specific stretches of genetic code and editing DNA. Researchers have used the tool to erase a genetic mutation that causes hypertrophic cardiomyopathy in human embryos.

Essential Frailty Toolset outperforms others in predicting mortality after TAVR, SAVR

Compared with six other scales that measure frailty, one called the Essential Frailty Toolset stands out for its ability to predict mortality 30 days after two types of valve replacement surgery. It can also predict worsening disability at one year, according to a new study.

Stroke is increasing in younger populations—but why?

With recent research suggesting that strokes among younger people are becoming more prevalent, healthcare professionals are looking into why.

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Printing 3D hearts

3D printers have created the darnedest things: acoustic guitars that strum and guns that shoot, women’s high-heeled shoes, lights, clocks and even custom-fitted fabric.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.