Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Shutdown imperils studies’ progress

The New York Times reports that the government shutdown has crippled clinical trial activity at the National Institutes of Health. Only 12 patients have been enrolled since Oct. 1. Normally enrollment averages 200 new patients a week.

October 10, 2013

Atherotech presents latest evidence showing how comprehensive lipid testing can help improve cardiovascular disease outcomes

New research reveals the advantages of new, more accurate risk assessment methodologies over the basic lipid panel. Atherotech Diagnostics Lab, a leading clinical reference laboratory specializing in advanced cardiometabolic testing and disease management solutions, will highlight recent evidence for improved cardiovascular disease assessment and prevention at the eighth annual Cardiometabolic Health Congress (CMHC) October 2-5, at the Sheraton Hotel in Boston.    

October 1, 2013

Ohio State's heart program names 2013 Schottenstein Laureate

The Ohio State University Wexner Medical Center's Heart and Vascular Center has named Dr. Garret FitzGerald, professor of Medicine and Pharmacology; chair of the Department of Pharmacology and director of the Institute for Translational Medicine and Therapeutics at the Perelman School of Medicine at University of Pennsylvania, the recipient of the 2013 Jay and Jeanie Schottenstein Prize in Cardiovascular Sciences.

September 26, 2013

Study comparing stroke therapies receives $2 million national research grant

An American Heart Association/American Stroke Association sponsored study comparing which stroke therapies work best has received a $2 million research award from the Patient-Centered Outcomes Research Institute (PCORI).

September 26, 2013

Bayer's investigational drug riociguat granted FDA orphan drug designation for treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension

Bayer HealthCare today announced that the U.S. Food and Drug Administration's (FDA) Office of Orphan Products Development has granted two separate orphan drug designations for its investigational, oral medication riociguat, proposed trade name Adempas®, for the treatment of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). The Orphan Drug Designation program provides orphan status to drugs and biologics that are defined as those intended for the safe and effective treatment, diagnosis or prevention of rare diseases and disorders that affect fewer than 200,000 people in the U.S., or that affect more than 200,000 persons but are not expected to recover the costs of developing and marketing a treatment drug.

September 26, 2013

Amarin announces enrollment of the REDUCE-IT cardiovascular outcomes study surpasses 6,000 patients

Amarin Corporation plc (Nasdaq:AMRN), a biopharmaceutical company focused on the commercialization and development of therapeutics to improve cardiovascular health, announced today that the number of patients enrolled in the company's REDUCE-IT cardiovascular outcomes study of Vascepa(R) (icosapent ethyl) capsules has surpassed 6,000.

September 26, 2013

Six visionary health leaders named Canada’s 2014 Hall of Fame inductees

The Canadian Medical Hall of Fame is proud to announce the 2014 inductees. Their passion and innovative, visionary leadership has improved health worldwide. The six inductees announced today will join the ranks of 101 laureates who have gone before them in receiving this prestigious national honour.

September 24, 2013

Atherotech Diagnostics Lab bolsters Research efforts with addition of Abate as Chief Clinical Officer

Atherotech Diagnostics Lab, a leading clinical reference laboratory specializing in cardiometabolic testing and disease management solutions, announces the addition of Gerard Abate, M.D., as the company’s Chief Clinical Officer.

September 20, 2013

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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