Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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Prosthetic-patient mismatch after TAVR much less likely among Asian patients

Patient outcomes, it seems, are not significantly impacted by this trend. 

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Pre-TAVR pulmonary artery dilatation helps identify high-risk patients

Imaging-based PAD may provide value as a noninvasive alternative to right heart catheterization. 

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TTVR patients see consistent improvements in their daily lives

Researchers evaluated 115 patients before and one month after undergoing transcatheter tricuspid valve repair, sharing their findings in JACC: Cardiovascular Interventions

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Pressure-regulated THV deployment could provide significant value

Overall, researchers found, this method was “simple, reproducible, safe and effective.”

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What new valve-in-valve TAVR data tell us about valve durability

Age, diabetes and smoking were all also found to be “significant predictors” of reduced valve durability among SAVR patients.

SAVR a valuable treatment option for asymptomatic patients with severe AS

Early valve replacement was associated with improved outcomes in a new study published in Circulation.

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SAVR associated with 'substantial' survival rates

The procedure is especially effective when treating younger, low-risk patients. 

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Certain patients with chronic kidney disease face a higher risk of death after TAVR

No such trend was reported among patients with end-stage kidney disease.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.