Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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AHA, Edwards collaborate on new structural heart initiative

A new structural heart disease initiative from the American Heart Association and Edwards Lifesciences will aim to raise patient awareness of valve diseases while enriching patient education and engagement.

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Long-term survival poor in patients with moderate, severe AS

Both severe and moderate aortic stenosis, when left untreated, were associated with poor long-term survival in a large-scale study of Australian heart patients.

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SAPIEN 3 valve cleared for use in low-risk patients in Europe

Edwards Lifesciences announced Nov. 6 that it had received expanded CE mark approval in Europe for the use of its SAPIEN 3 transcatheter heart valve, a tool designed to facilitate TAVI in patients who don’t want to undergo open-heart surgery.

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Cardiology’s Challenge for the 2020s: Turning the Trend on Rising Mortality

The latest numbers on cardiovascular deaths put the focus on innovative ways to point the trend line down again.

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PCHA, children’s hospitals unite to promote transparency in CV surgical outcomes

Children’s hospitals across the U.S. are backing a national effort by the Pediatric Congenital Heart Association to improve transparency in the reporting of cardiac surgical outcomes.

Public reporting of AVR outcomes linked to decreased access

An increase in public reporting of aortic valve surgery outcomes has been tied to a decrease in AVR access for patients with infective endocarditis—the unintended consequence of a push for greater transparency in healthcare.

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TAVR linked to better long-term health status than SAVR

Patients with severe aortic stenosis who undergo TAVR enjoy a minor but significant sustained health benefit that isn’t mirrored in patients who opt for surgical AVR, according to research reported at TCT 2019 in San Francisco.

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TMVR with MitraClip increases life expectancy—at a cost

An economic analysis of COAPT data suggests edge-to-edge TMVR with the MitraClip device is a more affordable long-term treatment option than guideline-directed medical therapy alone for patients with severe secondary MR—but the steep cost of an index TMVR procedure might eclipse that benefit.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.