Vascular & Endovascular

This channel includes news on non-coronary vascular disease and therapies. These include peripheral artery disease (PAD), abdominal and thoracic aortic aneurysm (AAA and TAA), aortic dissection, pulmonary embolism (PE), critical limb ischemia (CLI), carotid artery and stroke interventions, venous interventions, deep vein thrombosis (DVT), and interventional radiology therapies. The focus on most of these therapies is minimally invasive, catheter-based procedures performed in a cath lab.

Home BP measurements may predict cardiovascular risk better

Self-measured blood pressure readings may be better predictors of cardiovascular issues or death than conventional blood pressure measurements, except among people with severe hypertension, according to a study published in the January issue of PLOS Medicine.

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Bioresorbable scaffolds show early promise in peripheral arteries

Bioresorbable drug-eluting scaffolding appears to be safe and effective in patients with iliac and femoral artery lesions, based on six-month results in the first-in-man ESPRIT trial presented Jan. 22 at the International Symposium on Endovascular Therapy in Miami Beach, Fla. 

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Covidien drops renal denervation program

Covidien pulled the plug on its renal denervation initiative, citing “slower than expected development of the renal denervation market.”

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Mediterranean diet may hold off PAD in high-risk patients

The Mediterranean diet may lower the risk of peripheral artery disease (PAD), according to results published in a research letter in the Jan. 22-29 issue of JAMA.

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Commonly used carotid stent systems found to be safe

Three common carotid stenting systems used in the U.S. were associated with low rates of adverse events, a study published online Jan. 15 in JACC: Cardiovascular Interventions found.

Daiichi Sankyo submits SAVAYSATM (edoxaban) tablets New Drug Application to the U.S. FDA for once-daily use for stroke risk reduction in atrial fibrillation and for the treatment and prevention of recurrence of venous thromboembolism

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that the New Drug Application (NDA) for its investigational, oral, once-daily direct factor Xa-inhibitor SAVAYSATM (edoxaban) Tablets has been submitted to the U.S. Food and Drug Administration (FDA). In the U.S., Daiichi Sankyo is seeking approval for edoxaban for the reduction in risk of stroke and systemic embolic events (SEE) in patients with non-valvular atrial fibrillation (NVAF), as well as for the treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE) and for the prevention of recurrence of symptomatic venous thromboembolism (VTE). SAVAYSA is the proposed brand name for edoxaban if approved for marketing in the U.S.

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Guidelines help docs manage patients on novel anticoagulants

Although the novel oral anticoagulants dabigatran, rivaroxaban and apixaban offer alternatives to warfarin to prevent strokes in patients with atrial fibrillation, physicians may still need guidance on how to manage them.

SYMPLICITY HTN-3 falls short on effectiveness

The pivotal SYMPLICITY HTN-3 clinical trial designed to evaluate the safety and efficacy of renal denervation as a treatment for uncontrolled hypertension failed to meet its primary efficacy endpoint.

Around the web

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.