Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

Experts offer guidelines on circulatory support devices

An international and multidisciplinary team of experts has developed guidelines to assist physicians who treat patients with mechanical circulatory support devices (MCSDs). The executive summary with recommendations was published in the February issue of the Journal of Heart and Lung Transplantation.

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Statins unlikely to increase diabetes risk in some patients

Patients who do not have risk factors for diabetes are unlikely to develop the disease due to statin use, and although statins may increase the rate of new onset diabetes in patients at high risk of the disease, the benefits of reducing cardiovascular events outweigh the complications of diabetes, according to one meta-analysis.

HF: Can observation units reduce readmissions?

There is consensus that reducing hospital admissions and readmissions for heart failure (HF) is critical, but not on the best path to follow to reach those goals.

Polypill proves cost-effective, even in poorer nations

A polypill designed to reduce the risk of cardiovascular disease would be cost-effective in Latin America, even in countries with low gross national incomes, according to an analysis published in the January issue of Health Affairs.

FDA panel favors diabetes drug despite CV safety concerns

An FDA advisory panel recommended on a 10-5 vote approval for canagliflozin (Invokana, Janssen Research & Development) to treat type 2 diabetes in adult patients. But the panel also expressed concerns about the drug’s cardiovascular safety. In a separate vote on cardiovascular safety, the panel voted 8-7.

Merck suspends global availability of Tredaptive

Merck, known as MSd outside the U.S. and Canada, is taking steps to suspend the availability of nicotinic acid/laropiprant (Tredaptive) modified-release tablets worldwide.

VTE prophylaxis underutilized, even in high-risk patients

Patients hospitalized for medical reasons who are at risk of developing venous thromboembolism (VTE) rarely receive either pharmacologic or nonpharmacologic prophylactic treatment to prevent the condition.

Two antihypertensive + NSAID drugs may take toll on kidneys

Physicians who prescribe a combination of two antihypertensive drugs to their patients may want to be extra vigilant if non-steroidal anti-inflammatory drugs (NSAIDs) are added to a patient’s regimen. A study published Jan. 8 in BMJ found a triple therapy combination was associated with increased risk of acute kidney injury, with a twofold increased risk in the first 30 days of use.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.