Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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Genetic variants key in regulating appetite—for better or worse

Two studies published April 18 in the journal Cell have shined new light on the role genetics can play in developing obesity—or protecting against it.

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Framingham Heart Study lands $38M grant for 6 more years of research

The 71-year-old Framingham Heart Study has received $38 million from the National Heart, Lung, and Blood Institute to fund a new six-year study into the biology of aging.

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Novel antiplatelet could circumvent bleeding risk for stroke patients

The first study to test an experimental antiplatelet compound in humans found the therapy inhibited clot formation without increasing bleeding, suggesting it could avoid that dangerous side effect of other clot-preventing drugs.

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Metformin reduces left ventricular mass in nondiabetic patients with CAD

The popular diabetes drug metformin reversed left ventricular hypertrophy (LVH) in a randomized trial of patients with coronary artery disease but without diabetes, suggesting a potential new use for the medication.

PCI use, survival trending up for elderly STEMI patients with cardiogenic shock

Percutaneous coronary intervention is being offered to a greater proportion of older adults with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock over the past two decades—a trend that’s been paralleled by declining mortality rates, according to a study in the Journal of the American College of Cardiology.

Researchers: Urban, rural hospitals should have different standards for acute stroke care

Three physicians published an editorial in Stroke proposing that tertiary healthcare centers in cities be held to stricter standards for performing endovascular thrombectomy (EVT) than their rural counterparts.

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Genetic variant linked to chemotherapy-induced cardiomyopathy

The same genetic variants that have been uncovered in patients with two other types of cardiomyopathy are also present in an uncommonly high proportion of people with cancer therapy-induced cardiomyopathy (CCM), researchers reported in Circulation.

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Hydrogel capsules cleared by FDA to help with weight loss

The FDA has cleared Gelesis100 hydrogel capsules to be used as a weight management aid alongside diet and exercise in adults with body mass indexes (BMIs) ranging from 25 to 40, according to an April 14 press release from the product’s manufacturer.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.