New research from the University of Michigan has found that targeting inflammation in patients with venous thromboembolism could reduce rates of morbidity and mortality.

Researchers in Germany have developed a risk prediction score that strongly correlated with mortality in patients who suffer from cardiogenic shock following an acute MI.

American Regent announced on April 24 that the first patients had enrolled in a phase 3 trial evaluating an investigational heart failure medication.

From 1998 through 2013, the standardized incidence of infective endocarditis in New York and California remained stable between 7.6 and 7.8 cases per 100,000 persons each year, according to a retrospective database analysis. During that same period, the adjusted mortality risk related to infective endocarditis decreased 2 percent per year.

A registry analysis found that approximately one-third of patients who currently have acute coronary syndrome would have qualified for the IMPROVE-IT trial, which enrolled patients between 2005 and 2010.

Acute ischemic stroke hospitalizations rates increased among adults from 35 and 44 years old between 2003 and 2012, according to a database analysis.

The need for permanent pacemakers in patients with severe aortic stenosis who undergo transcatheter aortic valve replacement (TAVR) remains a complication, even as TAVR expands into lower-risk groups. That may prove to be a limitation, especially with younger patients who may have decades of life ahead of them.

Cardiovascular Systems recently announced the first patient had enrolled in the company’s ECLIPSE trial, which is evaluating its Diamondback 360 coronary orbital atherectomy system.