Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

FDA approves Boston Scientific’s quadripolar leads

The FDA approved Boston Scientific’s Acuity X4 quadripolar left ventricular leads on Feb. 23.

High-dose tirofiban during PCI is associated with significant reduction in all-cause mortality

A meta-analysis of 41 randomized clinical trials found that patients who received high-dose bolus tirofiban (Aggrastat, Medicure, Inc.) during PCI had a significant reduction in all-cause mortality compared with those who received eptifibatide or heparin.

Stenting and endarterectomy have similar outcomes in asymptomatic patients with severe carotid stenosis

During a five-year follow-up period, asymptomatic patients with severe carotid stenosis had similar rates of stroke and survival whether they underwent carotid artery stenting with embolic protection or carotid endarterectomy.

After stroke, Pioglitazone reduces risk of MI or subsequent stroke

After a median follow-up period of nearly five years, patients who received pioglitazone following a recent ischemic stroke or transient ischemic attack (TIA) had a lower risk of stroke or MI compared with a placebo group, according to a multicenter, double-blind trial.

Untreated hypertension leads to increased risk of intracerebral hemorrhage

People with untreated hypertension have a nine-fold higher risk of having an intracerebral hemorrhage regardless of race compared with those who are receiving treatment, according to a prospective, multicenter, case-control study.

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Hospital reimbursement for alteplase does not match up with increased costs

During the past decade, the cost of alteplase increased 111 percent, although reimbursement to hospitals for the clot-busting medication increased only 8 percent, according to an analysis.

DOJ reaches settlements with 51 hospitals for allegedly improperly implanting ICDs

The Department of Justice (DOJ) announced on Feb. 17 that it had reached settlements worth a total of more than $23 million with 51 hospitals in 15 states for allegedly improperly implanting implantable cardioverter defibrillators (ICDs) cardiac devices in Medicare patients. The claims were allegations, and the DOJ did not determine the hospitals were liable, according to a news release.

FDA approves St. Jude Medical’s pacing technology, leads and quartet test

The FDA approved St. Jude Medical’s MultiPoint pacing technology, quadripolar pacing Quartet LV leads and programmer-based Auto VectSelect Quartet Test on Feb. 17.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.