Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

Evidence doesn't support higher SBP goal, panel members argue

Although the Eighth Joint National Committee recently recommended raising the systolic blood pressure (SBP) goal from 140 mm Hg to 150 in people 60 years of age and older without diabetes mellitus or chronic kidney disease, five members of the panel disagreed in a viewpoint published online Jan. 14 in Annals of Internal Medicine. They argued that there was not sufficient evidence to increase the target SBP.

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Dense coronary artery plaque may lower heart disease risk

The denser coronary artery plaque is, the lower the risk may be of coronary heart disease and cardiovascular disease, according to a study published in the Jan. 15 issue of JAMA. This finding suggests that the current method of predicting risk, the Agatson coronary artery calcium score, may need to be re-evaluated.

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Options when proper care & reimbursement don’t align

What options do physicians and hospitals have when reimbursement rules are out of sync with current clinical guidelines and appropriate use criteria? Cardiologists used implantable cardioverter-defibrillators (ICDs) to illustrate this disconnect in the Jan. 7-14 issue of the Journal of the American College of Cardiology.

Hospital quality tied to racial disparity in post-CABG deaths

Nonwhite patients are more likely to die after CABG than white patients, and this disparity may be due in part to blacks’ poorer access to high-quality hospitals, a study published online Jan. 8 in JAMA Surgery found. Other unexplained factors may also contribute to the racial differences.

DOJ subpoenas Aegerion over Juxtapid

Aegerion Pharmaceuticals confirmed that it is under a federal magnifying glass again. The company disclosed in a financial statement that it was subpoenaed by the Department of Justice (DOJ) over its cholesterol drug, lomitapide.

Vorapaxar, rivaroxaban up for review

The FDA’s Cardiovascular and Renal Drugs Advisory Committee faces a full docket of applications for treatments for acute coronary syndrome and other diseases in January and February.

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Guidelines help docs manage patients on novel anticoagulants

Although the novel oral anticoagulants dabigatran, rivaroxaban and apixaban offer alternatives to warfarin to prevent strokes in patients with atrial fibrillation, physicians may still need guidance on how to manage them.

SYMPLICITY HTN-3 falls short on effectiveness

The pivotal SYMPLICITY HTN-3 clinical trial designed to evaluate the safety and efficacy of renal denervation as a treatment for uncontrolled hypertension failed to meet its primary efficacy endpoint.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.