CRF announces late-breaking clinical trials for TCT 2024

The Cardiovascular Research Foundation (CRF) has announced the full lineup of late-breaking clinical trials and late-breaking clinical science scheduled for TCT 2024 in Washington, DC.

TCT 2024 takes place Oct. 27-30 at the Walter E. Washington Convention Center. This is the 36th annual Transcatheter Cardiovascular Therapeutics Conference. What started in 1988 as a gathering of 150 heart specialists is now widely regarded as one of interventional cardiology’s most important, influential conferences.

Topics to be discussed during the four-day event include transcatheter aortic valve replacement (TAVR) and other structural heart procedures, cerebral protection devices, pharmaceutical treatments and much more.

Late-breaking clinical trials at TCT 2024

Monday, October 28

Early TAVR

Transcatheter Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis: Results of the EARLY TAVR Trial.

This session will be presented by Philippe Genereux.

TAVR UNLOAD

Transcatheter Aortic Valve Replacement in Patients With Systolic Heart Failure and Moderate Aortic Stenosis.

This session will be presented by Nicholas M. Van Mieghem.

EVOLVED

Early Intervention in Patients With Asymptomatic Severe Aortic Stenosis and Left Ventricular Myocardial Fibrosis.

This session will be presented by Marc Dweck.

TCT 2023 late-breaking clinical trials

Tuesday, October 29

ECLIPSE

A Large-Scale, Randomized Trial of Orbital Atherectomy vs. Conventional Balloon Angioplasty in Severely Calcified Coronary Arteries Prior to DES Implantation.

This session will be presented by Ajay J. Kirtane.

CLEAR SYNERGY (OASIS 9)

A 2x2 Factorial Randomized Controlled Trial of Colchicine vs. Placebo, and Spironolactone vs. Placebo in Patients With Myocardial Infarction: Results of the Colchicine Factorial.

This session will be presented by Sanjit S. Jolly.

PEERLESS

Large-Bore Mechanical Thrombectomy vs. Catheter-Directed Thrombolysis for Treatment of Intermediate-Risk Pulmonary Embolism.

This session will be presented by Wissam A. Jaber.

SIRONA

Head-to-Head Comparison of Sirolimus- vs. Paclitaxel-Coated Balloon Angioplasty in the Femoropopliteal Artery.

This session will be presented by Ulf Teichgraeber.

 

Wednesday, October 30

TRISCEND II

Randomized Comparison of Transcatheter Valve Replacement vs. Optimal Medical Therapy for Severe Tricuspid Regurgitation

This session will be presented by Susheel K. Kodali and Suzanne V. Arnold.

ACURATE IDE

One-year Outcomes of Acurate neo2 vs. Approved TAVR Devices in All-risk patients with Severe AS. 

This session will be presented by Michael J. Reardon.

FAVOR III Europe

Quantitative Flow Ratio or Fractional Flow Reserve for Guiding Coronary Revascularization

This session will be presented by Birgitte Krogsgaard Andersen.

FLASH

Artificial Intelligence-Based Fully Automated Quantitative Coronary Angiography vs. Optical Coherence Tomography Guidance for Coronary Stent Implantation: A Multicenter, Randomized Controlled Non-Inferiority Trial

This session will be presented by Jung-Min Ahn.

 

Late-breaking clinical science at TCT 2024

Monday, October 28

DCB-BIF

Comparison of Noncompliant Balloon With Drug-Coated Balloon Angioplasty for Side Branch Stenosis After Provisional Stenting for Patients With True Coronary Bifurcation Lesions

This session will be presented by ShaoLiang Chen. 

HELP PCI

Early Administration of Heparin at First Medical Contact vs. in the Cath Lab for STEMI Patients Undergoing Primary Percutaneous Coronary Intervention: A Multicenter, Randomized Trial.

This session will be presented by Jing Chen.

DRAMI

Randomized Comparison of Puncture Success Rate Between Distal Radial Access and Transradial Access in Patients With ST-Elevation Myocardial Infarction

This session will be presented by Jun-Won Lee.       

INFINITY-SWEDEHEART Complex PCI

1-Year and Landmark 6–12 Month Clinical Outcomes Among Patients With Complex Lesion Subsets Treated With DynamX Bioadaptor Compared to a Contemporary Drug Eluting Stent

This session will be presented by David Erlinge.

CONFIRM-2

Artificial Intelligence Enabled Quantitative CT Assessment of Atherosclerosis and Major Adverse Events: A Multi-Center International Registry

This session will be presented by Alexander Van Rosendael.

 

Tuesday, October 29

Co-STAR

Colchicine in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Double-Blind Randomized Controlled Trial

This session will be presented by Thomas Pilgrim.

ACCESS TAVI

Randomized Comparison of Strategies for Vascular Access Closure After Transcatheter Aortic Valve Implantation

This session will be presented by Tobias Rheude.    

PROTECTED TAVR: US Subgroup

Cerebral Embolic Protection in the U.S. Cohort of the PROTECTED TAVR Randomized Trial

This session will be presented by Raj Makkar.

RHEIA/PARTNER Pooled Analysis in Women

Transcatheter vs. Surgical Aortic Valve Replacement in Women: A Pooled Analysis of the RHEIA and PARTNER 3 Trials

This session will be presented by Didier Tchetche.

ALIGN-AR 2-Year

Two-Year Outcomes of Transcatheter Aortic Valve Replacement With JenaValve Trilogy in High Surgical Risk Patients With Moderate-to-Severe or Severe Native Aortic Regurgitation.

This session will be presented by Torsten P. Vahl.

 

Wednesday, October 30

TARGET IV

International Multicenter Randomized Assessment of the Firehawk Rapamycin-eluting Coronary Stent System

This session will be presented by Olivier F. Bertrand.          

TARGET DAPT

Prospective, Multicenter, Open-Label, Randomized Controlled Trial of 3-Month vs. 12-Month Dual Antiplatelet Therapy After Implantation of the Biodegradable Polymer Firehawk Sirolimus-eluting Coronary Stent

This session will be presented by Junbo Ge.

CLEAR-IE

Outcomes of Percutaneous Mechanical Aspiration in Right-Sided Infective Endocarditis: A Multicenter Registry

This session will be presented by Abdallah El Sabbagh.

CLASP IID 2 Year

RCT and Registry: Two-Year Outcomes of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation

This session will be presented by Raj Makkar.

MATTERHORN: Atrial MR Subgroup

Transcatheter Repair Versus Surgery in Atrial Mitral Regurgitation: Results From the MATTERHORN Trial. This session will be presented by Stephan Baldus.

 

More information on TCT 2024

Additional details about these late-breaking sessions are available here

Click here to read through Cardiovascular Business coverage of TCT 2023 in San Francisco, which included live session coverage as well as a series of exclusive video interviews.

Michael Walter
Michael Walter, Managing Editor

Michael has more than 18 years of experience as a professional writer and editor. He has written at length about cardiology, radiology, artificial intelligence and other key healthcare topics.

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