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New gene therapy may help protect the hearts of patients with Friedreich's ataxia

Video interview with Ronald Crystal, MD, chair, Department of Genetic Medicine at Weill Cornell Medicine, presented late-breaking findings on a first in-human, virus-delivered gene therapy trial to stop cardiomyopathy death in patients with Friedreich Ataxia (FA). #ACC #ACC26

A majority of deaths from Friedreich's ataxia are associated with heart complications. A new treatment years in the making could provide some much-needed relief.

  • Read more about New gene therapy may help protect the hearts of patients with Friedreich's ataxia

Long-term cardiac amyloidosis survival benefits seen in extension acoramidis trial

Prem Soman, MD, director of the Cardiac Amyloidosis Center and nuclear cardiology, and associate chief of cardiology at the University of Pittsburgh Medical Center Heart and Vascular Institute presented the late-breaking results from the long-term survival benefits and disease stabilization with the drug acoramidis in patients with transthyretin amyloid cardiomyopathy at ACC 2026.

Patient outcomes clearly show acoramidis reduces both all-cause mortality and cardiovascular hospitalizations, but the study also reinforced the importance of early diagnosis and prompt medical therapy. 
 

  • Read more about Long-term cardiac amyloidosis survival benefits seen in extension acoramidis trial

Johnson & Johnson launches faster PFA system in Europe

Johnson & Johnson announced the launch of its new Varipulse Pro pulsed field ablation (PFA) system in Europe following CE mark approval. It is five times faster at ablation delivery at a cooler temperature than the previous version.

The new version of the PFA system is five times faster than the current catheter to improve workflow.

  • Read more about Johnson & Johnson launches faster PFA system in Europe

FDA clears way for IDE pivotal trial of the Topaz tricuspid valve replacement system

The U.S. Food and Drug Administration (FDA) has approved an investigational device exemption (IDE) to conduct a pivotal clinical trial for TRiCares Topaz transcatheter tricuspid valve replacement (TTVR) system in the U.S. The TTVR system uses two stent frames, one for the valve and one to engage the annulus with a membrane shirt between them to enable flexing of the outer ring to better seal against regurgitation.expansing stents

The TRiCares Topaz uses a unique two-stent frame valve prosthesis for better sealing and flexibility.

  • Read more about FDA clears way for IDE pivotal trial of the Topaz tricuspid valve replacement system

Deepak Bhatt discusses some of the most impactful trials at ACC 2026

To unpack the large number of lat-breaking trials at the American College of Cardiology 2026 meeting, Cardiovascular Business spoke in the above video interview with Deepak L. Bhatt, MD, MPH, MBA, FACC, FAHA, FESC, MSCAI, director of the Mount Sinai Fuster Heart Hospital, who highlighted several studies he felt had the most scientific impact. This included a mix of drug, device and strategy trials pointing to advances in cardiology. #ACC #ACC26

Bhatt describes a mix of drug, device and strategy trials pointing to advances in cardiovascular science.
 

  • Read more about Deepak Bhatt discusses some of the most impactful trials at ACC 2026

Screening and treatment for chronic kidney disease in heart disease patients needs to be expanded

Damaged Organ

The risk associated with under-recognized CKD emerged early, highlighting the need for screening soon after a CAD diagnosis so that cardio-renal protective drugs can be started much earlier.

  • Read more about Screening and treatment for chronic kidney disease in heart disease patients needs to be expanded

Arizona cardiology practice paying $3.85M to resolve lawsuit after data breach

money cybersecurity ransomware health IT data breach hacker

The 2023 incident potentially gave an attacker access to the names, addresses and Social Security numbers of thousands of heart patients.

  • Read more about Arizona cardiology practice paying $3.85M to resolve lawsuit after data breach

FDA approves another GLP-1 pill for weight loss

heart drugs with stethoscope

The approval, made as part of a special FDA pilot program, took just 50 days.

  • Read more about FDA approves another GLP-1 pill for weight loss

Cardiologist was fired for speaking out about racist texts, private jet misuse, lawsuit claims

A gavel and a stethoscope

An interventional cardiologist believes he was targeted and terminated for being outspoken about a series of incidents at his hospital. 

  • Read more about Cardiologist was fired for speaking out about racist texts, private jet misuse, lawsuit claims

Hospital sues cardiology practice for alleged breach of contract, ending years-long partnership

broken relationship broken contract

The cardiovascular care of thousands of Missouri patients is suddenly up in the air. The heart of the issue is a practice's alleged interest in opening up a new private equity-backed clinic.  

  • Read more about Hospital sues cardiology practice for alleged breach of contract, ending years-long partnership

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