AI gaining ground in electrophysiology, but clinicians still run the show

 

Artificial intelligence (AI) is moving rapidly into cardiac electrophysiology (EP), helping clinicians detect disease, automate routine tasks and analyze complex cardiac data. However, physicians will remain central to decisions that require clinical judgment and an understanding of the patient beyond the medical record.

That was a key message from Sanjiv Narayan, MD, MBChB,MSc, director of the Electrophysiology Research and Atrial Fibrillation Program and co-founder of the Stanford Arrhythmia Center at Stanford Medicine, during presentations at ESC Congress 2026.

"I think that AI is at an incredible inflection point," Narayan told Cardiovascular Business in a new video interview. "It's on everybody's lips. We have areas where there's no question AI will totally disrupt and do things better than we've ever done, and better than we could have imagined."

On the other hand, he said AI's usefulness varies considerably depending on whether the available data are sufficient to answer a clinical question. When all the necessary information is contained within an ECG, for example, AI can determine whether AFib is present with a high degree of reliability. Similar applications can help analyze images and other data where the information needed for a decision is readily available.

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Where AI is not so good is when a diagnosis depends on information outside the image or test. Patient age, medical history, timing of symptoms and other clinical circumstances can fundamentally change interpretation, Narayan said, making human judgment still quite important.

In EP, he sees significant potential for AI in remote monitoring and automated clinical workflows. Electronic health records could identify patients who are due for AFib screening or other preventive services, reducing the chance that busy clinicians overlook guideline-based recommendations.

AI also could assist physicians by documenting patient encounters. Systems that listen to conversations, summarize visits and identify medications or follow-up issues could reduce the administrative burden associated with electronic medical records and allow clinicians to spend more time interacting with patients. Narayan emphasized, however, that these summaries and recommendations still require appropriate oversight.

The limitations become particularly apparent when AI is expected to replace the clinician-patient relationship. Narayan cited research involving healthcare chatbots in areas such as stroke rehabilitation and early stroke detection, where the systems were not sufficiently accurate and patients reported concerns about a lack of empathy and standardized responses.

"I think that there's a way that we interact as humans that you can't write as an equation. And because of that, it's hard to train an AI to do it. If you were to just take all the texts on the internet, it would be very hard to thread those needles in a way that we would do in a natural human conversation. So I think there's always a big chance of missing something if we don't have the human in the loop," he explained.

EP data a perfect fit for AI applications

Narayan expects AI adoption in EP to continue growing for applications such as measuring AFib burden, identifying patients who may warrant consideration of anticoagulation and flagging individuals who could be at elevated risk of sudden cardiac death. AI is also beginning to assist with interpretation of complex electrical signals during AFib and ventricular tachycardia ablation procedures, although its current clinical adoption remains modest.

However, he said AI implementation for EP is still young, but the nature of EP clinical data makes it ripe for AI applications.

"If we continue to develop those models, I am incredibly excited about that potential," Narayan said. "It's a great time to be in computational work in cardiology, and what I love about this is so much of what we do was built for computational modeling. It was built for AI. It was built to be turned into physics."

A good example of this is the development of digital twin technology, where AI can generate a model of a patient's heart based on their testing and imaging data. This could provide another major avenue for AI to expand in cardiology. These models could eventually help clinicians understand individual patients in greater detail and potentially guide procedures and therapies. Narayan said the technology remains under development and will need to advance alongside traditional research and clinical trials.

For now, Narayan said the most appropriate path is to use AI where it can reliably automate data-driven tasks while retaining clinicians for decisions requiring context, judgment and communication. He said humans still need to be kept in the loop and make the final; decisions on care, and that is not something he said that will change anytime soon. 

Dave Fornell is a digital editor with Cardiovascular Business and Radiology Business magazines. He has been covering healthcare for more than 16 years.

Dave Fornell has covered healthcare for more than 17 years, with a focus in cardiology and radiology. Fornell is a 5-time winner of a Jesse H. Neal Award, the most prestigious editorial honors in the field of specialized journalism. The wins included best technical content, best use of social media and best COVID-19 coverage. Fornell was also a three-time Neal finalist for best range of work by a single author. He produces more than 100 editorial videos each year, most of them interviews with key opinion leaders in medicine. He also writes technical articles, covers key trends, conducts video hospital site visits, and is very involved with social media. E-mail: [email protected]

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