Acute Coronary Syndromes

Acute coronary syndrome (ACS) is most commonly caused by a heart attack (myocardial infarction) where blood flow to the heart is suddenly blocked. This is usually caused by a blood clot from a ruptured coronary artery atherosclerotic plaque. Other causes include spontaneous coronary artery dissection (SCAD), which most commonly occurs in women. ACS is usually treated in a cath lab with angioplasty and the placement of a stent to prop the vessel open.

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Odd physical signs sometimes warn of heart disease

Many people don’t know they have cardiovascular disease until they end up in the hospital with myocardial infarction. But a few strange external signs could signal all is not right with the heart, an anatomy professor noted in The New Zealand Times.

Amgen Receives Positive CHMP Opinion Recognizing That Repatha® (evolocumab) Prevents Heart Attacks And Strokes

Amgen (NASDAQ:AMGN) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion to include a new indication in the Repatha® (evolocumab) label for adults with established atherosclerotic cardiovascular disease (myocardial infarction, stroke or peripheral arterial disease) to reduce cardiovascular risk by lowering LDL-C levels.

Study adds to understanding about utility of ultra-sensitive cardiac troponin measurement in diagnosing and predicting cardiovascular syndromes

ALAMEDA, Calif., March 13, 2018 — Cardiac troponin I (cTnI) concentrations measured with the Singulex ultrasensitive cTnI assay, powered by Single Molecule Counting technology, were associated with a higher prevalence of coronary artery disease (CAD) and independently predicted cardiovascular events in patients with obstructive and non-obstructive CAD, according to a study published in the Journal of the American Heart Association.

Generic clopidogrel works as well as more expensive brand-name counterpart

Generic clopidogrel was equally effective as the brand-name antiplatelet Plavix for an older population with acute coronary syndrome (ACS), according to a study published in Circulation: Cardiovascular Quality and Outcomes.

Short-term DAPT linked to more heart attacks than extended treatment

Long-term dual antiplatelet therapy (DAPT) should remain the standard of care following implantation of drug-eluting stents, suggests research presented March 12 at the American College of Cardiology’s annual scientific session and published simultaneously online in The Lancet.

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TCT paradox: Patients more likely to survive MI during interventional cardiology conference

Patients hospitalized with acute myocardial infarction (AMI) actually fare better when some of the top minds in interventional cardiology are away at the annual Transcatheter Cardiovascular Therapeutics (TCT) meeting, suggests a study published March 9 in the Journal of the American Heart Association.

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Positivity could be key to better outcomes for those with chest pain

The mind-body connection includes a concept that our thoughts, feelings and beliefs can impact our physical health. Could those suffering from chronic angina improve outcomes by changing their outlook? A new study to be presented at the American College of Cardiology’s 67th Annual Scientific Session suggests so.

Antidepressant prescriptions post-MI linked to higher mortality risk

An observational study of nearly 9,000 heart attack patients found people discharged from the hospital with a prescription for antidepressants had a 66 percent greater chance of all-cause death within one year.

Around the web

Several key trends were evident at the Radiological Society of North America 2024 meeting, including new CT and MR technology and evolving adoption of artificial intelligence.

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.