Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Study links alcohol consumption and cardiovascular disorders

Consuming a lot of alcohol has long been associated with heart problems, but a new study offers an uncharted perspective on “wet” counties versus “dry” counties and how living in either can affect cardiovascular health.

June 21, 2016

Adolescent obesity a strong indicator for middle-age heart failure

Having a higher-than-normal body mass index (BMI) as a teenager could be an indicator that men will experience heart failure in middle age. 

June 17, 2016

Combination of diabetes and heart failure more deadly than previously realized

Patients who suffer from type 2 diabetes and coronary heart disease could be in worse shape than doctors previously thought, say the authors of a new study published in the journal Diabetes Care. 

June 13, 2016

Loneliness and isolation lead to a 30% increased risk in heart disease, stroke

A study published by Heart found that loneliness and social isolation are linked to a 30 percent increased risk of having a stroke or developing coronary artery disease, the two leading causes of death for men and women.

April 22, 2016

Experimental heart failure medication meets primary endpoint in phase 2b trial

Vericel Corp. announced on March 10 that its experimental drug to treat advanced heart failure due to ischemic dilated cardiomyopathy met the primary endpoint in a phase 2b clinical trial.

March 10, 2016

Self-care does not improve mortality in chronic heart failure patients

Patients with chronic heart failure and high scores on a global self-care scale had similar rates of long-term, all-cause mortality compared with those with low scores, according to a secondary analysis from two observational prospective studies. 

March 8, 2016
Abbott has received an expanded FDA indication approval for its CardioMEMs HF System, making the solution available for patients in earlier stages (NYHA stage II) of heart failure (HF). New FDA indication for CardioMEMS

Model finds the CardioMEMS device is cost-effective for heart failure patients

A model-based study found that patients with chronic heart failure who used the CardioMEMS device had reductions in hospitalizations and increases in quality-adjusted life-years (QALYs) and costs.

February 12, 2016

Novartis agrees to pay-for-performance agreements with insurers to cover heart failure drug

Novartis has entered into a pay-for-performance agreement with Cigna to cover sacubitril/valsartan (Entresto), a twice-daily oral medication to treat patients with heart failure and reduced ejection fraction. Aetna also signed a value-based agreement with Novartis based on the drug having similar results as shown in clinical trials, according to a Reuters report.

February 10, 2016

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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