Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Acute heart failure drug trial presents mixed findings

New research on the experimental drug ularitide, which is designed to decrease adverse effects of acute heart failure, has left cardiologists deciphering findings that are simultaneously disappointing and encouraging.

Storm's coming? Heart attacks on the rise post Hurricane Katrina

Ten years after Hurricane Katrina hit New Orleans, hospital admissions for heart attacks in the city were three times higher than they were before the storm, according to new research.

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Meat-heavy diet could lead to heart failure in older women

A diet full of steaks, hamburgers and hot dogs could be putting older women at higher risk for heart failure.

Mouse heart map clues researchers in on human heart maturation

Understanding the genetic programming of a mouse heart helps determine how human congenital heart defects are formed.  

Genetic mutation linked to rare heart disease

Researchers at the University of Colorado Anschutz Medical campus have discovered a link between a genetic mutation and left ventricular noncompaction.

FDA approves Medtronic’s CRT device for heart failure patients

The FDA approved the Claria MRI quad cardiac resynchronization therapy (CRT) defibrillator for patients with heart failure.

New Post-Hoc Analysis Supports YOSPRALA™ Efficacy And Safety In Previous Heart Attack Patients Who Need Daily Aspirin Therapy To Prevent A Second Cardiovascular Event

MISSISSAUGA, Ontario, Nov. 14, 2016 /PRNewswire/ --Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ) (TSX: ARZ) ("Aralez" or the "Company") today announced new data for YOSPRALA™, a recently FDA-approved prescription fixed-dose combination of aspirin, an anti-platelet agent, and omeprazole, a proton pump inhibitor (PPI), demonstrated significantly lower rates of gastric and duodenal ulcers compared to aspirin alone among patients with a history of myocardial infarction at risk for secondary cardiovascular events and gastrointestinal problems related to aspirin therapy at the annual American Heart Association Scientific Sessions.

A midday snooze could increase the risk for heart disease

Napping for more than 60 minutes a day increases the risk of developing metabolic syndrome—a leading cause of heart disease. 

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Around the web

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Use of AI opportunistic screening in CT for cardiovascular disease

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

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New imaging protocols proposed to curb rise of cardiovascular infections

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