Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Dapagliflozin associated with reduced risk of worsening HF, CV mortality

The findings provide further support for the use of dapagliflozin as a new treatment option in HFrEF, regardless of race, the authors suggest. 

Tafamidis boosts survival for patients with transthyretin amyloid cardiomyopathy

This latest analysis tracked more than 300 patients for a median follow-up period of nearly five years.

Metoprolol demonstrates value as a treatment for obstructive hypertrophic cardiomyopathy

The small study, published in the Journal of the American College of Cardiology, compared patient outcomes associated with metoprolol and a placebo. 

Decades of data help researchers recommend the optimal HFrEF treatment

The new analysis, published in JACC: Heart Failure, included data from 75 different studies.

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What new research tells us about HIV and heart failure

Patients with HIV have a greater chance of developing heart failure, according to new data published in Mayo Clinic Proceedings.

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Heart attack survivors with kidney issues face a greater risk of heart failure

The study included more than 200,000 MI survivors—and nearly 25% presented with one form of renal failure or another. 

KCCQ-12 scores a valuable asset for managing patients with acute HF

The scores can help predict a patient's short- and long-term risk of adverse outcomes. 

DOACs outperform VKAs among cardiac amyloidosis patients with HF, AFib

Outcomes from patients prescribed apixaban, rivaroxaban or dabigatran were compared with outcomes from patients given warfarin. 

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