Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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SGLT2 inhibitors lower risk of HFpEF, new meta-analysis confirms

Patients taking SGLT2 inhibitors were 22% less likely to die from heart-related causes.

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Cardiac rehabilitation benefits heart failure patients—but for how long?

The study tracked 2,876 patients hospitalized for acute HF or deteriorating chronic HF.

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In-hospital mortality more common among COVID-19 patients with heart failure

The authors also noted that cardiac complications such as myocarditis, MI and new-onset heart failure were rare during hospitalization for COVID-19.

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Aspirin use may increase your risk of heart failure

Doctors may not want to prescribe aspirin to patients presenting with obesity, high blood pressure, diabetes or a number of other risk factors.

What we know about COVID-19 and cardiogenic shock

The full analysis was published in Circulation: Heart Failure. 

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Is depression a warning sign for heart failure?

The study, published in the Journal of the American Heart Association, examined how certain symptoms related to depression might be associated with a person's risk of HFpEF and HFrEF.

Empagliflozin provides consistent benefits for HFpEF patients

Researchers took a fresh look at data from the EMPEROR-Preserved trial, sharing their findings in Circulation.

Stem cell therapy for heart failure lowers risk of adverse outcomes

“Cell therapy has the potential to change how we treat heart failure,” one researcher said.

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Around the web

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