Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Sacubitril/valsartan improves short-term health outcomes in those with HFrEF

The combo drug sacubitril/valsartan was associated with early improvements in health status in a study of nearly 4,000 patients with HFrEF.

November 1, 2019

Metformin lowers risk of HF hospitalization in those with T2D

Metformin use is linked to a lower risk of hospitalization for heart failure in patients with type 2 diabetes, a paper in the Journal of the American Heart Association confirms.

October 31, 2019

Machine learning improves patient selection for CRT

A novel machine learning algorithm improved patient selection for CRT in a study of nearly 1,000 heart failure patients, representing an opportunity to optimize care and spare certain individuals from a pricey procedure that might not benefit them.

October 22, 2019

FDA OKs dapagliflozin to reduce risk of HF hospitalization in adults with T2D

Pharmaceutical company AstraZeneca announced Oct. 21 that its drug Farxiga—or dapagliflozin—was approved by the FDA to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes.

October 21, 2019

1 in 5 patients in cardiac rehab are depressed, anxious or stressed

Around one in five heart patients in cardiac rehabilitation are depressed, anxious or stressed, according to a new study published in the European Journal of Preventive Cardiology.

October 10, 2019

Analysis adds to evidence of an ‘obesity paradox’ in heart failure

Evidence published in BMJ Heart last month supports the idea of an “obesity paradox” in heart failure, further complicating a long-running debate as to whether extra weight can be cardioprotective in patients with established CVD.

October 7, 2019
A doctor speaking with a patient

Communication training improves end-of-life discussions between HF patients, physicians

A 90-minute communication skills course improved conversations about ICD deactivation and goals of care between clinicians and their patients, according to the recently published results of the WISDOM study.

September 25, 2019

Cardiac amyloidosis increasingly common in US

New research suggests the incidence of cardiac amyloidosis in the U.S. is trending up, bringing with it high rates of morbidity and mortality.

September 20, 2019
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