Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Scientists dissect the reasons behind sudden cardiac death in triathlons

Triathlons could be risky for athletes with heart disease, potentially leading to cardiac arrest or sudden death, according to a new Minneapolis Heart Institute Foundation study.

Heart disease, tobacco leading causes of global deaths in 2016

Chronic diseases, including heart disease and diabetes, caused 72 percent of deaths worldwide in 2016, according to the recently released Global Burden of Disease study.

MyoKardia Presents Additional Positive Data from Phase 2 PIONEER-HCM Study of Mavacamten (Formerly MYK-461) at the Heart Failure Society of America’s 21st Annual Scientific Meeting

New Positive Data on Secondary and Exploratory Endpoints Consistent with Previously Reported Topline Results 

New heart failure treatment increases ejection fraction by 38% in 1st clinical patient

The first clinical patient to undergo a new, less invasive treatment for heart failure has been discharged from University Hospital Zurich in Switzerland and is recovering well, according to a press release from BioVentrix.

Zywie Selected for Startup Showcase at 10th Annual Venture Atlanta

Zywie’s Next-Generation Remote Cardiac Monitoring Solution Revolutionizing Decades-Old Solution 

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Sudden cardiac death a significant contributor to mortality in women, regardless of CAD status

Sudden cardiac death is a significant contributor to mortality in women, regardless of presence of coronary artery disease (CAD), according to a six-year study published in the Journal of the American Heart Association.

Researchers link aldosterone, plasma renin activity to increased risk for CVD in black Americans

Increased levels of aldosterone and plasma renin activity (PRA) are associated with greater risk of cardiovascular disease (CVD) and all-cause mortality among blacks in the U.S., according to a community-based study.

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Hearts with improving LVSD can be safely transplanted

Donor hearts with left ventricular systolic dysfunction (LVSD) can be revived and transplanted as successfully as other hearts, according to a study in the Journal of the American College of Cardiology.

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Around the web

Health Imaging
Use of AI opportunistic screening in CT for cardiovascular disease

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Health Imaging
New imaging protocols proposed to curb rise of cardiovascular infections

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.