Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

The USPSTF changed the low-dose aspirin recommendations for cardiovascular disease prevention in April 2022 by suggesting patients over age 60 without history of CVD should not take it and people 40-60 should only take it if there are other risk factors.

VIDEO: USPSTF official discusses new low-dose aspirin recommendations

Michael J. Barry, MD, vice chair of the U.S. Preventive Services Task Force, gave Cardiovascular Business an overview of the new recommendations.

May 6, 2022
Patients who take diuretics, renin-angiotensin system (RAD) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs) at the same time face a much higher risk of developing acute kidney injury (AKI)

Combining certain BP medications with NSAIDs linked to kidney damage—acetaminophen seen as a safer option

A team of researchers used computer science and mathematics to study the "triple whammy" of diuretics, RAS inhibitors and NSAIDs.

May 5, 2022

How the science behind COVID-19 vaccines could transform care for heart attack patients

A technique seen in the Pfizer-BioNTech and Moderna COVID-19 vaccines may be able to help heart cells repair themselves, according to new research out of the Netherlands. 

May 5, 2022
mavacamten

FDA approves mavacamten for obstructive hypertrophic cardiomyopathy

The FDA’s approval was based on data from the EXPLORER-HCM trial, which showed that mavacamten was superior to a placebo for treating obstructive HCM and associated with no significant long-term, treatment-related adverse events.

May 2, 2022
Pills

Statin reduces risk for non-obstructive CAD patients but no significant risk reduction for aspirin

The results of a study published in Radiology: Cardiothoracic Imagincall into question the value of initiating aspirin therapy in certain instances.

April 29, 2022
USPSTF updates its stance on aspirin use to prevent CVD, sees no benefit for patients 60 or older.

USPSTF updates its stance on aspirin use to prevent CVD, sees no benefit for patients 60 or older

These recommendations, the group emphasized, do not include patients with a history of CVD or those who are already taking aspirin for another reason.

April 26, 2022
The new recall includes five lots of medications distributed from December 2019 to April 2022. Similar products were also recalled back in March for the same reason. The FDA recalled Accupril from Pfizer.

FDA announces another recall of common hypertension medication due to potential cancer risk

The new recall includes five lots of medications distributed from December 2019 to April 2022. Similar products were also recalled back in March for the same reason.

April 25, 2022
insulin_glargine_1.jpg

FDA announces new insulin recall due to potential labeling issue

The recall is focused on a single batch distributed from December 2021 to March 2022.

April 14, 2022

Around the web

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

Kate Hanneman, MD, explains why many vendors and hospitals want to lower radiology's impact on the environment. "Taking steps to reduce the carbon footprint in healthcare isn’t just an opportunity," she said. "It’s also a responsibility."

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