Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

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This latest shortage involves dobutamine, an injectable medication often prescribed for advanced heart failure and cardiogenic shock. It is also a central component of dobutamine stress echocardiography (DSE), a test used to evaluate patients with severe aortic stenosis.

A new supply issue hits cardiology: 5 recommendations for cardiologists during the dobutamine shortage

The shortage could lead to significant issues for cardiologists. The American College of Cardiology provided some words of wisdom on the ongoing issue.  

anticoagulation UNC Charlotte RNA DNA

Programmable RNA-DNA anticoagulant fibers may provide a better balance between blood clots and bleeding risks

“We can learn from nature, but we have built something that has never been introduced before,” one researcher said. 

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“We need an answer now”: Cardiologist awarded $2.3M to study cannabis use and heart health in people living with HIV

The four-year analysis will use cardiac MRI scans to closely monitor the heart health of people living with HIV who regularly use cannabis to treat their symptoms. 

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Catheter-directed thrombolysis boosts survival rates for submassive pulmonary embolism

The new meta-analysis included data from nearly 10,000 patients. 

The American Medical Association (AMA) Board of Delegates approved a policy calling on payers to reimburse for the drug regadenoson and not to employ payment policies that push for cardiologists to change the drug they use for pharmacologic stress for one that is considered less safe. The policy was adopted at the AMA 2022 meeting. #AMA #AMA175 #AMAmtg #ASNC

AMA supports reimbursement for pharmacologic stress agent regadenoson

The American Medical Association Board of Delegates approved a policy calling on payers to reimburse for the drug regadenoson and not to employ payment policies that push for cardiologists to change the drug they use for pharmacologic stress for one that is considered less safe.

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Statin use may slow progression of arterial stiffness

Continuous and high-adherent statin users had lower baseline arterial stiffness, which also grew more slowly over time. 

Predicting the impact of new heart attack medications

The study's authors hope their equations can make a significant impact on patient care in the years ahead. 

NOACs comparable to warfarin when treating AFib patients with valvular heart disease

Researchers examined the clinical impact of treating valvular AFib with dabigatran instead of warfarin. 

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Around the web

Health Imaging
Use of AI opportunistic screening in CT for cardiovascular disease

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Health Imaging
New imaging protocols proposed to curb rise of cardiovascular infections

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.

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