Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

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Statin use may slow progression of arterial stiffness

Continuous and high-adherent statin users had lower baseline arterial stiffness, which also grew more slowly over time. 

Predicting the impact of new heart attack medications

The study's authors hope their equations can make a significant impact on patient care in the years ahead. 

NOACs comparable to warfarin when treating AFib patients with valvular heart disease

Researchers examined the clinical impact of treating valvular AFib with dabigatran instead of warfarin. 

Novavax NVX-CoV2373 COVID-19 vaccine myocarditis

FDA committee backs Novavax's COVID-19 vaccine despite heart damage concerns

The committee's approval comes days after the FDA shared details on a small number of trial participants who developed myocarditis or pericarditis after receiving the vaccine.  

RAAS inhibitors lower risk of aneurysm rupture among patients with high blood pressure

Researchers also noted that uncontrolled hypertension, exposure to second-hand smoke and untreated type 2 diabetes were all associated with a greater rupture risk.

metformin chemodynamic therapy type 2 diabetes Nano Research

A new use for metformin? Popular type 2 diabetes medication may also improve cancer and infection therapies

Metformin appears to improve the impact of chemodynamic therapy, according to a new analysis in Nano Research. 

Empagliflozin may reverse vascular aging, lower CVD risk

The SGLT2 inhibitor is already known as an effective medication for both type 2 diabetes and heart failure.

Anagrelide capsules FDA recall Teva Pharmaceuticals USA

FDA announces recall of platelet-reducing medication due to risk of clotting or other adverse cardiovascular outcomes

The medication failed a routine dissolution test, meaning it could lose its effectiveness. 

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Around the web

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Use of AI opportunistic screening in CT for cardiovascular disease

Ron Blankstein, MD, professor of radiology, Harvard Medical School, explains the use of artificial intelligence to detect heart disease in non-cardiac CT exams.

Health Imaging
New imaging protocols proposed to curb rise of cardiovascular infections

Eleven medical societies have signed on to a consensus statement aimed at standardizing imaging for suspected cardiovascular infections.