Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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Guidelines on fat intake may need revision

The long-standing recommendations to decrease the intake of saturated fat and increase intake of polyunsaturated fatty acids in order to reduce the risk of heart disease may warrant reconsideration, based on a study published online March 18 in Annals of Internal Medicine. The study found little evidence to support this guideline.

FDA approves new indication for apixaban

The FDA has approved a supplemental New Drug Application for the anticoagulant apixaban for the prevention of deep vein thrombosis, which may lead to pulmonary embolism in patients who have undergone hip or knee replacement surgery.

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Gestational diabetes may up risk of atherosclerosis

Women who develop gestational diabetes but have no history of type 2 diabetes or metabolic syndrome may be at increased risk for subclinical atherosclerosis, regardless of whether they are obese before pregnancy or not, based on the findings of a study published online March 12 in the Journal of the American Heart Association.

Combat exposure may increase risk of heart disease

Military deployments may increase the risk for coronary heart disease among U.S. service members and veterans, a study published online March 11 in Circulation found.

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‘One-Stop Shop’ Clinics Treat Heart Disease, Diabetes in Tandem

With cardiovascular disease being the No. 1 killer of Americans and type 2 diabetes one of its most common comorbidities, a number of clinics see coordinated, comprehensive care as a way to treat both conditions.

Q&A | ACC.14: Late-breaker Lessons

The late-breaking clinical trials at the American College of Cardiology (ACC) scientific sessions often draw large crowds.

Technically inoperable patients fare best after TAVR

Transcatheter aortic valve replacement (TAVR) patients who are inoperable because of technical reasons have better outcomes than TAVR patients who are clinically inoperable, a finding that could help identify patients likely to reap the greatest benefit from the procedure.

FDA places another recall on Ranbaxy’s statin

The FDA once again issued a recall on Ranbaxy’s generic statin, this time after a pharmacist spotted a 20-mg tablet in a sealed bottle of atorvastatin calcium at 10 mg doses.

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